Silver sulfadiazine

Silver sulfadiazine Structure
Silver sulfadiazine structure
Common Name Silver sulfadiazine
CAS Number 22199-08-2 Molecular Weight 357.137
Density 1.496g/cm3 Boiling Point 512.6ºC at 760 mmHg
Molecular Formula C10H9AgN4O2S Melting Point 285 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 263.8ºC
Symbol GHS07
GHS07
Signal Word Warning

Silver sulfadiazine: an antibacterial agent for topical use in burns. A review of the literature.

Scand. J. Plast. Reconstr. Surg. 18(1) , 119-26, (1984)

Topical antibacterial treatment is of major importance in the burn patient. Silver sulfadiazine is an effective agent with low toxicity and few side effects. Deposition of silver in tissues, and absorption of sulfadiazine are both minimal. Present and future ...

[The use of a topical antibacterial agent (silver sulfadiazine) on soft-tissue wounds].

Minerva Chir. 45(9) , 677-81, (1990)

Reducing the quantitative level of bacterial contamination in an open, acute or chronic, soft tissue wound below the critical level of 10(5) bacteria per gram of viable tissue is essential to delayed primary closure. First step in the management of the contam...

A review of the dosimetry of 1% silver sulfadiazine cream in burn wound treatment.

J. Burn Care Rehabil. 15(3) , 213-23, (1994)

A review of the periodical literature relating to burn topical antibacterial agents as listed in the Cumulated Index Medicus from January 1, 1965, through November 30, 1992, as well as bound volumes and unpublished material reveals that the optimal dose and m...

The side effects of silver sulfadiazine.

J. Burn Care Res. 30(3) , 464-70, (2009)

Silver sulfadiazine cream has an enviable safety record in burn treatment. However, it side effects, exemplified by allergic reactions to its sulfadiazine moiety, silver staining of the treated burn wound, hyperosmolality, methemoglobinemia, and hemolysis due...

Silver sulfadiazine for the treatment of partial-thickness burns and venous stasis ulcers.

J. Am. Acad. Dermatol. 66(5) , e159-65, (2012)

For decades silver-containing antibiotics such as silver sulfadiazine (SSD) have been applied as standard topical therapy for patients with partial-thickness burns and venous stasis ulcers. This evidence-based review intends to answer the following research q...

Impaired wound healing in diabetes: the rationale for clinical use of hyaluronic acid plus silver sulfadiazine.

Minerva Med. 103(6) , 533-9, (2012)

Diabetes-related chronic cutaneous lesions are a serious and common problem, as well as a major cause for hospital admissions, although no general consensus has been reached on the best available treatment for this frequent pathological condition. The primary...

Use of silver sulfadiazine in Stevens-Johnson syndrome.

Ann. Pharmacother. 28(6) , 736-7, (1994)

Diagnostic challenges of assessing the depth of burn injuries overlying intricate coloured tattoos.

J. Plast. Reconstr. Aesthet. Surg. 67(7) , e186-7, (2014)

Myth: silver sulfadiazine is the best treatment for minor burns.

West. J. Med. 175(3) , 205-6, (2001)