Montelukast sodium
Montelukast sodium structure
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Common Name | Montelukast sodium | ||
|---|---|---|---|---|
| CAS Number | 151767-02-1 | Molecular Weight | 608.165 | |
| Density | N/A | Boiling Point | 750.5ºC at 760mmHg | |
| Molecular Formula | C35H35ClNNaO3S | Melting Point | 115 °C(dec.) | |
| MSDS | Chinese USA | Flash Point | 407.7ºC | |
| Symbol |
GHS05, GHS08 |
Signal Word | Danger | |
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Does desloratadine alter the serum levels of montelukast when administered in a fixed-dose combination?
Laryngoscope 123(11) , 2610-4, (2013) The aim of this study was to investigate the serum levels of montelukast when administered alone or in combination with desloratadine.A prospective crossover study.Twenty-three healthy volunteers were investigated in two sessions. Volunteers were given 10 mg ... |
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Add-on therapy with montelukast in the treatment of Henoch-Schönlein purpura.
Pediatr. Int. 56(3) , 315-22, (2014) Previous studies suggested that leukotrienes (LT) were involved in the pathogenesis of Henoch-Schönlein purpura (HSP). This study investigated the efficacy of an add-on therapy with montelukast in the treatment of HSP.In this four-center, double-blind, placeb... |
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Effects of montelukast on the healing of ischemic colon anastomoses.
Am. J. Surg. 206(4) , 502-8, (2013) The aim of this study was to examine whether treatment with montelukast, a selective leukotriene antagonist, would affect anastomotic healing in a reperfused colon rat model with remote ischemia/reperfusion injury.Rats (n = 12 per group) were intraperitoneall... |
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Histopathologic evaluation of anti-ulcerogenic effect of montelukast in indomethacin-induced experimental ulcer model.
Turk. J. Gastroenterol. 24(2) , 88-92, (2013) The effects of anti-ulcerogenic drugs are dependent on the increase in prostaglandin production and reduction in leukotriene production in the gastric mucosa. Montelukast is an anti-asthmatic drug, a selective reversible cysteinyl leukotriene D4 receptor anta... |
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Chemopreventive effect of montelukast in n-nitroso n-methyl urea induced mammary carcinogenesis in female Sprague-Dawley rats.
Indian J. Pharmacol. 45(3) , 286-8, (2013) The objective of the study was to evaluate the chemopreventive effect of montelukast sodium; selective reversible cysteinyl leukotriene D4-receptor antagonist in N-nitroso N-methyl urea (NMU) induced mammary carcinogenesis in virgin female Sprague-Dawley rats... |
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Immune reconstitution inflammatory syndrome Kaposi sarcoma in the liver manifesting as acute obstructive hepatitis: another potential role for montelukast?
Int. J. STD AIDS 24(2) , 156-8, (2013) Immune reconstitution inflammatory syndrome has been described in Kaposi sarcoma, but does not usually manifest as acute hepatitis. We describe a case of rapid obstructive jaundice after initiation of antiretroviral therapy, in which the liver biopsy confirme... |
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Is montelukast indicated for treatment of chronic rhinosinusitis with polyposis?
Laryngoscope 124(8) , 1735-6, (2014)
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Anaphylaxislike cholinergic urticaria.
Can. Fam. Physician 59(7) , 745-6, (2013)
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Impact of montelukast on asthma associated with rhinitis, and other triggers and co-morbidities.
J. Asthma 51(1) , 1-17, (2014) Rhinitis and other specific triggers or co-morbidities (tobacco exposure, excess weight, aspirin sensitivity or heredity factors) are frequently associated with uncontrolled asthma. Asthma associated with these exacerbating factors appears to be related to an... |
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Effect of a cysteinyl leukotriene receptor antagonist on experimental emphysema and asthma combined with emphysema.
Am. J. Respir. Cell. Mol. Biol. 50(1) , 18-29, (2014) The incidence of overlapping bronchial asthma and chronic obstructive pulmonary disease has increased in recent years. Cysteinyl leukotrienes (CysLTs) play an important role in asthma, and the type 1 CysLT receptor (CysLT1R) is expressed by many inflammatory ... |