sodium picosulfate
sodium picosulfate structure
|
Common Name | sodium picosulfate | ||
|---|---|---|---|---|
| CAS Number | 10040-45-6 | Molecular Weight | 499.42 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H13NNa2O8S2.H2O | Melting Point | 272 - 275ºC | |
| MSDS | N/A | Flash Point | N/A | |
|
A validated bowel-preparation tolerability questionnaire and assessment of three commonly used bowel-cleansing agents.
Dig. Dis. Sci. 58(4) , 926-35, (2013) Bowel-cleansing studies are frequently underpowered, poorly designed, and with subjective assessments. Consensus on tolerability of the bowel-cleansing agents is thus lacking. This study developed and validated a bowel-preparation tolerability questionnaire a... |
|
|
Is mechanical bowel preparation in laparoscopic radical prostatectomy beneficial? An analysis of a Japanese national database.
BJU Int. 112(2) , E76-81, (2013) WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: Recently, the ineffectiveness of bowel mechanical preparation prior to colorectal surgery was focused on. Although its effectiveness was widely accepted in laparoscopic prostatectomy, the data were li... |
|
|
An interview study analysing patients' experiences and perceptions of non-laxative or full-laxative preparation with faecal tagging prior to CT colonography.
Clin. Radiol. 68(5) , 472-8, (2013) To compare patients' experiences of either non- or full-laxative bowel preparation with additional faecal tagging and subsequent computed tomographic (CT) colonography using in-depth interviews to elicit detailed responses.Patients who received CT colonograph... |
|
|
A pilot study on the efficacy of Picolax given as a four-week course for the treatment of refractory constipation.
Hong Kong Med. J. 18(5) , 388-94, (2012) OBJECTIVES. Although Picolax (sodium picosulphate and magnesium citrate) has been widely documented for use in bowel preparation, there is limited literature on its efficacy in the treatment of constipation. Refractory constipation is a more difficult situati... |
|
|
Obesity does not affect sodium picosulphate bowel preparation.
Intern. Med. J. 42(12) , 1324-9, (2012) A previous study utilising oral polyethylene-glycol by Borg et al. concluded that obesity is an independent predictor of inadequate bowel preparation at colonoscopy.To compare bowel preparation quality between obese and non-obese individuals as assessed by Bo... |
|
|
Colonoscopy with mucosal biopsies in young rats: a model for experimental gastroenterology.
Mol. Med. Report. 7(6) , 1757-60, (2013) Endoscopy is an important tool in the diagnosis, follow-up and management of several gastrointestinal diseases. In experimental studies, the course and progression of gastrointestinal lesions are followed by sacrificing animals at specific time intervals and ... |
|
|
Time for individualized colonoscopy bowel-prep regimens? A randomized controlled trial comparing sodium picosulphate and magnesium citrate versus 4-liter split-dose polyethylene glycol.
J. Gastrointestin. Liver Dis. 22(2) , 129-34, (2013) Good bowel cleansing is essential to achieving optimal endoscopic evaluation of the colon. There are many different regimens available, but none have shown consistently superior results in achieving a clean colon. We compared the efficiency of two regimens wi... |
|
|
Serial monitoring of the physiological effects of the standard Pico-Salax® regimen for colon cleansing in healthy volunteers.
Can. J. Gastroenterol. 26(7) , 424-8, (2012) Sodium picosulfate⁄magnesium oxide⁄citric acid (Pico-Salax, Ferring Inc, Canada) is used widely in Canada and other countries for colon cleansing before colonoscopy. It is a low-volume osmotic⁄stimulant agent with the potential to deplete intravascular volume... |
|
|
High-sensitivity liquid chromatography-tandem mass spectrometry method for the simultaneous determination of sodium picosulfate and its three major metabolites in human plasma.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 915-916 , 1-7, (2013) Sodium picosulfate (PICO-Na) is a member of the polyphenolic group of stimulant laxatives. Its major metabolites in humans are its active aglycone BHPM (bis-(p-hydroxyphenyl)-pyridyl-2-methane), the monoglucuronide (M1) and the monosulfate (M2) of BHPM. A sen... |
|
|
Laxative-free CT colonography.
Br. J. Radiol. 85(1016) , e410-5, (2012) The aim of this study was to determine if the introduction of faecal tagging to CT colonography (CTC) made the examination easier to tolerate or reduced the number of false-positives.Our department changed bowel preparation for CT colonography from Picolax (F... |