5-Bromo-2,4-dichloropyrimidine
5-Bromo-2,4-dichloropyrimidine structure
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Common Name | 5-Bromo-2,4-dichloropyrimidine | ||
|---|---|---|---|---|
| CAS Number | 36082-50-5 | Molecular Weight | 227.874 | |
| Density | 2.0±0.1 g/cm3 | Boiling Point | 287.5±20.0 °C at 760 mmHg | |
| Molecular Formula | C4HBrCl2N2 | Melting Point | 29-30 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 127.7±21.8 °C | |
| Symbol |
GHS05, GHS06 |
Signal Word | Danger | |
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Pseudo-cyclization through intramolecular hydrogen bond enables discovery of pyridine substituted pyrimidines as new Mer kinase inhibitors.
J. Med. Chem. 56(23) , 9683-92, (2013) Abnormal activation or overexpression of Mer receptor tyrosine kinase has been implicated in survival signaling and chemoresistance in many human cancers. Consequently, Mer is a promising novel cancer therapeutic target. A structure-based drug design approach... |
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Syntheses and optimization of new GS39783 analogues as positive allosteric modulators of GABA B receptors.
Bioorg. Med. Chem. Lett. 17(22) , 6206-11, (2007) The optimization of GS39783 into potent, selective, and safe positive allosteric modulators of GABA(B) receptors is presented. |
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Synthesis , 861, (2006)
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Pyrimidines. Part VIII. Halogeno-and hydrazino-pyrimidines. Chesterfield J, et al.
J. Chem. Soc. , 3478-3481, (1955)
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Synthesis 5 , 728-734, (2003)
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Synthesis of Various 5-Substituted Uracils. Peters D, et al.
J. Heterocycl. Chem. 27(7) , 2165-70, (1990)
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