Methyl isovanillate

Methyl isovanillate Structure
Methyl isovanillate structure
Common Name Methyl isovanillate
CAS Number 6702-50-7 Molecular Weight 182.173
Density 1.2±0.1 g/cm3 Boiling Point 327.7±22.0 °C at 760 mmHg
Molecular Formula C9H10O4 Melting Point 64-67ºC
MSDS Chinese USA Flash Point 132.8±15.8 °C
Symbol GHS07
GHS07
Signal Word Warning

Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk).

Bioorg. Med. Chem. Lett. 21 , 3152-3158, (2011)

Continued examination of substituted 6-arylquinazolin-4-amines as Clk4 inhibitors resulted in selective inhibitors of Clk1, Clk4, Dyrk1A and Dyrk1B. Several of the most potent inhibitors were validated as being highly selective within a comprehensive kinome s...