Diethyl chloromalonate

Diethyl chloromalonate Structure
Diethyl chloromalonate structure
Common Name Diethyl chloromalonate
CAS Number 14064-10-9 Molecular Weight 194.613
Density 1.2±0.1 g/cm3 Boiling Point 222.0±0.0 °C at 760 mmHg
Molecular Formula C7H11ClO4 Melting Point N/A
MSDS Chinese USA Flash Point 103.3±0.0 °C
Symbol GHS05 GHS07 GHS09
GHS05, GHS07, GHS09
Signal Word Danger

K2CO3-promoted domino reactions: construction of functionalized 2,3-dihydrobenzofurans and clofibrate analogues.

J. Org. Chem. 76(17) , 7222-8, (2011)

The K(2)CO(3)-catalyzed domino reactions (Michael alkylation, Mannich alkylation, and aldol alkylation) of salicylic aldehyde derivatives (2-hydroxyaryl-α,β-unsaturated ketones, 2-hydroxyarylnitroalkenes, 2-hydroxyarylimines, and salicylic aldehydes) and 2-ha...

Preparation of 2-amino-4(3H)-oxopyrimido[5,4-b] [1,4]thiazines (5-thiapterins) and their evaluation as cofactors for phenylalanine hydroxylase.

J. Med. Chem. 26(4) , 559-63, (1983)

Reaction of diethyl chloromalonate with beta-mercapto amines, 9, gave 1,4-thiazin-3-ones, 10, which were alkylated exclusively at the lactam oxygen with triethyloxonium tetrafluoroborate and subsequently condensed with guanidine to give the first reported 5-t...

Preparation of cycloaddition chemistry of thio-and selenocarbonyls derived from reaction of elemental sulfur and selenium with stabilized a-halo anions. Abelman MM.

Tetrahedron Lett. 32(50) , 7389-92, (1990)