Phenyl isothiocyanate
Phenyl isothiocyanate structure
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Common Name | Phenyl isothiocyanate | ||
|---|---|---|---|---|
| CAS Number | 103-72-0 | Molecular Weight | 135.186 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 221.0±9.0 °C at 760 mmHg | |
| Molecular Formula | C7H5NS | Melting Point | −21 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 87.8±0.0 °C | |
| Symbol |
GHS05, GHS06, GHS08 |
Signal Word | Danger | |
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Allyl isothiocyanate induces replication-associated DNA damage response in NSCLC cells and sensitizes to ionizing radiation.
Oncotarget 6(7) , 5237-52, (2015) Allyl isothiocyanate (AITC), a constituent of many cruciferous vegetables exhibits significant anticancer activities in many cancer models. Our studies provide novel insights into AITC-induced anticancer mechanisms in human A549 and H1299 non-small cell lung ... |
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Developing structure-activity relationships for the prediction of hepatotoxicity.
Chem. Res. Toxicol. 23 , 1215-22, (2010) Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification o... |
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A predictive ligand-based Bayesian model for human drug-induced liver injury.
Drug Metab. Dispos. 38 , 2302-8, (2010) Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predictive in vivo, in vitro, and in silico models to identify comp... |
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Proteomic analysis of the extracellular matrix in idiopathic pes equinovarus.
Mol. Cell Biochem. 401(1-2) , 133-9, (2015) Idiopathic pes equinovarus is a congenital deformity of the foot and lower leg defined as a fixation of the foot in adduction, supination, and varus. Although the pathogenesis of clubfoot remains unclear, it has been suggested that fibroblasts and growth fact... |
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Supplementation of l-Alanyl-l-Glutamine and Fish Oil Improves Body Composition and Quality of Life in Patients With Chronic Heart Failure.
Circ. Heart Fail. 8 , 1077-87, (2015) Skeletal muscle dysfunction and exercise intolerance are clinical hallmarks of patients with heart failure. These have been linked to a progressive catabolic state, skeletal muscle inflammation, and impaired oxidative metabolism. Previous studies suggest bene... |
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Pathway and time-resolved benzo[a]pyrene toxicity on Hepa1c1c7 cells at toxic and subtoxic exposure.
J. Proteome Res. 14(1) , 164-82, (2015) Benzo[a]pyrene (B[a]P) is an environmental contaminant mainly studied for its toxic/carcinogenic effects. For a comprehensive and pathway orientated mechanistic understanding of the effects directly triggered by a toxic (5 μM) or a subtoxic (50 nM) concentrat... |
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The anti-inflammatory secoiridoid glycosides from gentianae scabrae radix: the root and rhizome of Gentiana scabra.
J. Nat. Med. 69 , 303-12, (2015) Gentianae Scabrae Radix is a well-known traditional medicine that is used for the treatment of hepatitis, cholecystitis and inflammatory diseases. It consists mainly of secoiridoid glycosides, with representatives of gentiopicroside, sweroside and swertiamari... |
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Aroma improvement by repeated freeze-thaw treatment during Tuber melanosporum fermentation.
Sci. Rep. 5 , 17120, (2015) The aroma attributes of sulfurous, mushroom and earthy are the most important characteristics of the aroma of Tuber melanosporum. However, these three aroma attributes are absent in the T. melanosporum fermentation system. To improve the quality of the aroma,... |
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Investigation of dendriplexes by ion mobility-mass spectrometry.
Molecules 19(12) , 20731-50, (2014) Highly branched polyamidoamine (PAMAM) dendrimers presenting biological activities have been envisaged as non-viral gene delivery vectors. They are known to associate with nucleic acid (DNA) in non-covalent complexes via electrostatic interactions. Although t... |
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A systematic, comparative study on the beneficial health components and antioxidant activities of commercially fermented soy products marketed in China.
Food Chem. 174 , 202-13, (2014) The objectives of this study are to systematically assess the bioactive substances and overall antioxidant capacities of commercially fermented soy products and to find the relationships between the presence of beneficial components in different types of soyb... |