8-Thiooctanoic acid
8-Thiooctanoic acid structure
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Common Name | 8-Thiooctanoic acid | ||
|---|---|---|---|---|
| CAS Number | 74328-61-3 | Molecular Weight | 176.276 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 302.0±25.0 °C at 760 mmHg | |
| Molecular Formula | C8H16O2S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 136.4±23.2 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Synthesis of benzimidazole derivatives as potent β-glucuronidase inhibitors.
Bioorg. Chem. 61 , 36-44, (2015) Twenty five 4, 6-dichlorobenzimidazole derivatives (1-25) have been synthesized and evaluated against β-glucuronidase inhibitory activity. The compounds which actively inhibit β-glucuronidase activity have IC50 values ranging between 4.48 and 46.12 μM and sho... |
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Spastin binds to lipid droplets and affects lipid metabolism.
PLoS Genet. 11 , e1005149, (2015) Mutations in SPAST, encoding spastin, are the most common cause of autosomal dominant hereditary spastic paraplegia (HSP). HSP is characterized by weakness and spasticity of the lower limbs, owing to progressive retrograde degeneration of the long corticospin... |
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Characterization of Lipoyl Synthase from Mycobacterium tuberculosis.
Biochemistry 55 , 1372-83, (2016) The prevalence of multiple and extensively drug-resistant strains of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, is on the rise, necessitating the identification of new targets to combat an organism that has infected one-third of th... |
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A role for ubiquitin ligases and Spartin/SPG20 in lipid droplet turnover.
J. Cell Biol. 184 , 881-94, (2009) HECT (homologous to the E6AP C terminus) ubiquitin ligases have diverse functions in eukaryotic cells. In screens for proteins that bind to the HECT ubiquitin ligase WWP1, we identified Spartin, which is also known as SPG20. This protein is truncated in a neu... |
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Uptake of Marasmius oreades agglutinin disrupts integrin-dependent cell adhesion.
Biochim. Biophys. Acta 1860 , 392-401, (2015) Fruiting body lectins have been proposed to act as effector proteins in the defense of fungi against parasites and predators. The Marasmius oreades agglutinin (MOA) is a lectin from the fairy ring mushroom with specificity for Galα1-3Gal containing carbohydra... |
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Menaquinone-7 is specific cofactor in tetraheme quinol dehydrogenase CymA.
J. Biol. Chem. 287 , 14215-25, (2012) Little is known about enzymatic quinone-quinol interconversions in the lipid membrane when compared with our knowledge of substrate transformations by globular enzymes. Here, the smallest example of a quinol dehydrogenase in nature, CymA, has been studied. Cy... |
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Quantitative analysis of the native presynaptic cytomatrix by cryoelectron tomography.
J. Cell Biol. 188 , 145-56, (2010) The presynaptic terminal contains a complex network of filaments whose precise organization and functions are not yet understood. The cryoelectron tomography experiments reported in this study indicate that these structures play a prominent role in synaptic v... |
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Protein phosphatase 2A associates with and regulates atypical PKC and the epithelial tight junction complex.
J. Cell Biol. 158 , 967-78, (2002) Tight junctions (TJs) play a crucial role in the establishment of cell polarity and regulation of paracellular permeability in epithelia. Here, we show that upon calcium-induced junction biogenesis in Madin-Darby canine kidney cells, ABalphaC, a major protein... |
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Transient protection from heat-stress induced apoptotic stimulation by metastasis-associated protein 1 in pachytene spermatocytes.
PLoS ONE 6(10) , e26013, (2011) Deregulated thermal factors have been frequently implicated in the pathogenesis of male infertility, but the molecular basis through which certain responses are directed remain largely unknown. We previously reported that overexpression of exogenous Metastasi... |
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Synthesis, α-glucosidase inhibitory, cytotoxicity and docking studies of 2-aryl-7-methylbenzimidazoles.
Bioorg. Chem. 65 , 100-9, (2016) Benzimidazole analogs 1-27 were synthesized, characterized by EI-MS and (1)HNMR and their α-glucosidase inhibitory activities were found out experimentally. Compound 25, 19, 10 and 20 have best inhibitory activities with IC50 values 5.30±0.10, 16.10±0.10, 25.... |