TTHA

TTHA Structure
TTHA structure
Common Name TTHA
CAS Number 869-52-3 Molecular Weight 494.450
Density 1.5±0.1 g/cm3 Boiling Point 818.3±65.0 °C at 760 mmHg
Molecular Formula C18H30N4O12 Melting Point 232-233 °C(lit.)
MSDS USA Flash Point 448.7±34.3 °C
Symbol GHS07
GHS07
Signal Word Warning

Improving sensitivity in simultaneous determination of copper carboxylates by nonaqueous capillary electrophoresis.

J. Chromatogr. A. 1110(1-2) , 261-7, (2006)

A new method of nonaqueous capillary electrophoresis (NACE) with UV spectrophotometric detection was developed and optimized for the simultaneous determination of seven carboxylates (trans-1,2-diaminocyclohexane-N,N,N',N'-tetraacetic acid (CDTA), diethylenetr...

In vivo sodium chemical shift imaging.

Magn. Reson. Med. 23(1) , 77-88, (1992)

The shift reagents thulium(III) 1,4,7,10-tetraazacyclododecane N,N',N",N"'tetramethylenephosphonate (TmDOTP5-), and dysprosium(III)triethylenetetramine-hexaacetate (DyTTHA3-) are compared in this work for their uses in sodium chemical shift imaging (NaCSI). I...

Measured rates of fluoride/metal association correlate with rates of superoxide/metal reactions for Fe(III)EDTA(H2O)- and related complexes.

J. Am. Chem. Soc. 130(5) , 1727-34, (2008)

The effects of 10 paramagnetic metal complexes (Fe(III)EDTA(H2O)-, Fe(III)EDTA(OH)2-, Fe(III)PDTA-, Fe(III)DTPA2-, Fe(III)2O(TTHA)2-, Fe(III)(CN)6(3-), Mn(II)EDTA(H2O)2-, Mn(II)PDTA2-, Mn(II)beta-EDDADP2-, and Mn(II)PO4(-)) on F- ion 19F NMR transverse relaxa...

23Na NMR shift reagents enhance cardiac staircase effect in isolated perfused rat hearts.

NMR Biomed. 12(5) , 267-74, (1999)

The effects of the currently used (23)Na NMR shift reagents, dysprosium bis-triphosphate [Dy(PPP)(2)], dysprosium triethylenetriamine hexaacetate [Dy(TTHA)] and thulium 1,4,7, 10-tetraazacyclododecane-N,N',N",N"'-tetra(methylenephosphonate) [Tm(DOTP)] were st...

Kinetics of the exchange reactions between Gd(DTPA)2-, Gd(BOPTA)2-, and Gd(DTPA-BMA) complexes, used as MRI contrast agents, and the triethylenetetraamine-hexaacetate ligand.

Inorg. Chem. 50(8) , 3471-8, (2011)

The kinetics of ligand exchange reactions occurring between the Gd(DTPA), Gd(BOPTA), and Gd(DTPA-BMA) complexes, used as contrast agents in MRI, and the ligand TTHA, have been studied in the pH range 6.5-11.0 by measuring the water proton relaxation rates at ...

The effects of the NMR shift-reagents Dy(PPP)2, Dy(TTHA) and Tm(DOTP) on developed pressure in isolated perfused rat hearts. The role of shift-reagent calcium complexes.

J. Mol. Cell. Cardiol. 33(11) , 1945-56, (2001)

The 23Na NMR shift-reagent complexes (Dy(PPP)2, Dy(TTHA), and Tm(DOTP)) bind stoichiometric amounts of Ca2+. Thus, in perfused rat heart systems, a supplementation of Ca2+ is required to maintain the requisite extracellular free calcium concentration ([Ca(o)]...

Ischemic changes in myocardial ionic contents of the isolated perfused rat hearts as studied by NMR.

Mol. Cell Biochem. 119(1-2) , 109-20, (1993)

Using 31P-, 23Na- and 39K-NMR, we assessed ischemic changes in high energy phosphates and ion contents of isolated perfused rat hearts continuously and systematically. To discriminate intra- and extracellular Na+, a shift reagent (Dy(TTHA)3-) was used in 23Na...

Efficacy of liposome encapsulated triethylenetetraamine hexaacetic acid (TTHA) against cadmium intoxication: role of lipid composition.

Ind. Health 33(2) , 83-8, (1995)

Efficacy of Triethylenetetraamine hexaacetic acid (TTHA) encapsulated in liposomes having different lipid compositions was examined in animals pre-exposed to cadmium. Mice were injected with cadmium as cadmium (II) chloride 0.5 mg/kg b. wt. intraperitoneally ...

Direct measurement of increased myocardial cellular 23Na NMR signals in perfused guinea-pig heart induced by dihydroouabain and grayanotoxin-I.

Mol. Cell Biochem. 139(1) , 59-70, (1994)

The effects of the cardiac glycoside dihydroouabain (DHO), and the ericaceous toxin grayanotoxin-I (GTX-I) on myocardial cellular sodium (Nai) concentrations were investigated using sodium-23 nuclear magnetic resonance (23Na NMR) spectroscopy at 30 degrees C ...

Effect of triethylenepentaminehexaacetic acid on the renal damage in cadmium-treated Syrian hamsters.

Biol. Trace Elem. Res. 50(2) , 157-65, (1995)

Cadmium (Cd)-induced nephropathy was treated by triethylenepentaminehexaacetic acid (TTHA) in male Syrian hamsters. Hamsters injected three times a week with 3 mg/kg body wt CdCl2 showed proteinuria, urinary N-acetyl-beta-D-inglucosaminidase (NAG), and fracti...