5-FLUORO-2-HYDROXYPYRIMIDINE
5-FLUORO-2-HYDROXYPYRIMIDINE structure
|
Common Name | 5-FLUORO-2-HYDROXYPYRIMIDINE | ||
|---|---|---|---|---|
| CAS Number | 2022-78-8 | Molecular Weight | 114.07800 | |
| Density | 1.46g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C4H3FN2O | Melting Point | 170-174ºC | |
| MSDS | USA | Flash Point | N/A | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
|
Phase I clinical trial of 5-fluoro-pyrimidinone (5FP), an oral prodrug of 5-fluorouracil (5FU).
Invest. New Drugs 20(1) , 63-71, (2002) 5-Fluoro-Pyrimidinone (5FP) is an oral pro-drug of 5-Fluorouracil (5FU), and is converted to 5FU by hepatic aldehyde oxidase. Preclinically, 5FP demonstrated anti-tumor activity against colon 38 and P 388 leukemia models in mice. Using an accelerated titratio... |
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