Quetiapine Fumarate

Quetiapine Fumarate Structure
Quetiapine Fumarate structure
Common Name Quetiapine Fumarate
CAS Number 111974-72-2 Molecular Weight 441.54
Density N/A Boiling Point 556.5ºC at 760 mmHg
Molecular Formula C23H27N3O4S Melting Point 174-176°C
MSDS Chinese USA Flash Point 290.4ºC
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

The dopaminergic stabilizers pridopidine and ordopidine enhance cortico-striatal Arc gene expression.

J. Neural Transm. Gen. Sect. 121(11) , 1337-47, (2014)

The dopaminergic stabilizers pridopidine [4-(3-(methylsulfonyl)phenyl)-1-propylpiperidine] and ordopidine [1-ethyl-4-(2-fluoro-3-(methylsulfonyl)phenyl)piperidine] inhibit psychostimulant-induced hyperactivity, and stimulate behaviour in states of hypoactivit...

An understanding of modified release matrix tablets behavior during drug dissolution as the key for prediction of pharmaceutical product performance - case study of multimodal characterization of quetiapine fumarate tablets.

Int. J. Pharm. 484(1-2) , 235-45, (2015)

Motivation for the study was the lack of dedicated and effective research and development (R&D) in vitro methods for oral, generic, modified release formulations. The purpose of the research was to assess multimodal in vitro methodology for further bioequival...

Quetiapine for the treatment of cocaine use disorder.

Drug Alcohol Depend. 149 , 18-24, (2015)

Cocaine addiction continues to be a significant healthcare issue, yet there are no FDA approved medications for the treatment of cocaine use disorder within the United States.This 12-week, prospective, double-blind, randomized, placebo-controlled study examin...

Evaluation of human D-amino acid oxidase inhibition by anti-psychotic drugs in vitro.

Biosci. Trends 8(3) , 149-54, (2014)

It is of importance to determine whether antipsychotic drugs currently prescribed for schizophrenia exert D-amino acid oxidase (DAO)-inhibitory effects. We first investigated whether human (h)DAO can metabolize D-kynurenine (D-KYN) to produce the fluorescent ...