Tert-butyl (triphenylphosphoranylidene)acetate

Tert-butyl (triphenylphosphoranylidene)acetate Structure
Tert-butyl (triphenylphosphoranylidene)acetate structure
Common Name Tert-butyl (triphenylphosphoranylidene)acetate
CAS Number 35000-38-5 Molecular Weight 376.428
Density 1.1±0.1 g/cm3 Boiling Point 503.5±33.0 °C at 760 mmHg
Molecular Formula C24H25O2P Melting Point 152-155 °C(lit.)
MSDS Chinese USA Flash Point 271.4±45.7 °C
Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger

ELEMENTAL SELENIUM GENERATED BY THE PHOTOBLEACHING OF SELENOMEROCYANINE PHOTOSENSITIZERS FORMS CONJUGATES WITH SERUM MACROMOLECULES THAT ARE TOXIC TO TUMOR CELLS.

Phosphorus. Sulfur. Silicon Relat. Elem. 67 , 311, (1992)

Elemental selenium generated by the photobleaching of selenomerocyanine dyes forms conjugates with serum albumin and serum lipoproteins that are toxic to leukemia and selected solid tumor cells but well tolerated by normal CD34-positive hematopoietic stem and...

Inhibition of group IVA cytosolic phospholipase A2 by novel 2-oxoamides in vitro, in cells, and in vivo.

J. Med. Chem. 47 , 3615-3628, (2004)

The Group IVA cytosolic phospholipase A(2) (GIVA PLA(2)) is a particularly attractive target for drug development because it is the rate-limiting provider of proinflammatory mediators. We previously reported the discovery of novel 2-oxoamides that inhibit GIV...

Orally active aldose reductase inhibitors: indazoleacetic, oxopyridazineacetic, and oxopyridopyridazineacetic acid derivatives.

J. Med. Chem. 35 , 2155, (1992)

Benzothiazole side chains featured in zopolrestat (1a) and its congeners were incorporated into oxophthalazineacetic acid replacements, including indazole, pyridazinone, and pyridopyridazinone with a pendant acetic acid moiety. Potent aldose reductase inhibit...

J. Org. Chem. 57 , 2922, (1992)

Tetrahedron Lett. 35 , 4809, (1994)