trifluoroacetic acid

trifluoroacetic acid Structure
trifluoroacetic acid structure
Common Name trifluoroacetic acid
CAS Number 76-05-1 Molecular Weight 114.023
Density 1.535 Boiling Point 72 ºC
Molecular Formula C2HF3O2 Melting Point -15 °C
MSDS Chinese USA Flash Point -2.5±25.9 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

Studies on the catalytic domains of multiple JmjC oxygenases using peptide substrates.

Epigenetics 9(12) , 1596-603, (2015)

The JmjC-domain-containing 2-oxoglutarate-dependent oxygenases catalyze protein hydroxylation and N(ϵ)-methyllysine demethylation via hydroxylation. A subgroup of this family, the JmjC lysine demethylases (JmjC KDMs) are involved in histone modifications at m...

Molecular insights into shellac film coats from different aqueous shellac salt solutions and effect on disintegration of enteric-coated soft gelatin capsules.

Int. J. Pharm. 484(1-2) , 283-91, (2015)

The purpose of this investigation was to study the effect of using different salts of shellac on the disintegration properties of shellac-based enteric coatings. In the last two decades, shellac has been increasingly used as an aqueous solution for enteric co...

The adenylyl cyclase Rv2212 modifies the proteome and infectivity of Mycobacterium bovis BCG.

Folia Microbiol. (Praha) 60(1) , 21-31, (2014)

All organisms have the capacity to sense and respond to environmental changes. These signals often involve the use of second messengers such as cyclic adenosine monophosphate (cAMP). This second messenger is widely distributed among organisms and coordinates ...

Interactome analysis of the human respiratory syncytial virus RNA polymerase complex identifies protein chaperones as important cofactors that promote L-protein stability and RNA synthesis.

J. Virol. 89(2) , 917-30, (2015)

The human respiratory syncytial virus (HRSV) core viral RNA polymerase comprises the large polymerase protein (L) and its cofactor, the phosphoprotein (P), which associate with the viral ribonucleoprotein complex to replicate the genome and, together with the...

Studying the chemistry of cationized triacylglycerols using electrospray ionization mass spectrometry and density functional theory computations.

J. Am. Soc. Mass Spectrom. 25(8) , 1421-40, (2014)

Analysis of triacylglycerols (TAGs), found as complex mixtures in living organisms, is typically accomplished using liquid chromatography, often coupled to mass spectrometry. TAGs, weak bases not protonated using electrospray ionization, are usually ionized b...

Proteomic analysis of nasal epithelial cells from cystic fibrosis patients.

PLoS ONE 9(9) , e108671, (2014)

The pathophysiology of cystic fibrosis (CF) lung disease remains incompletely understood. New explanations for the pathogenesis of CF lung disease may be discovered by studying the patterns of protein expression in cultured human nasal epithelial cells (HNEC)...

Acetyltransferase p300/CBP associated Factor (PCAF) regulates crosstalk-dependent acetylation of histone H3 by distal site recognition.

ACS Chem. Biol. 10(1) , 157-64, (2015)

Epigenetic regulation is directed, in part, by the correlated placement of histone post-translational modifications, but the mechanisms controlling correlated modifications are incompletely understood. Correlations arise from crosstalk among modifications and...

To the novel paradigm of proteome-based cell therapy of tumors: through comparative proteome mapping of tumor stem cells and tissue-specific stem cells of humans.

Cell. Transplant. 23 Suppl 1 , S151-70, (2014)

We performed proteome mapping (PM), cataloging, and bioinformation analysis of protein lysates of human neural (CD133(+)) progenitor and stem cells (NPSCs) isolated from the olfactory sheath of a nose, multipotent mesenchymal (CD29(+), CD44(+), CD73(+), CD90(...

A proteomic approach to monitor the dynamic response of the female oviductal epithelial cell surface to male gametes.

J. Proteomics 113 , 1-14, (2014)

Sophisticated strategies to analyze cell surface proteins are indispensable to study fundamental biological processes, such as the response of cells to environmental changes or cell-cell communication. Herein, we describe a refined mass spectrometry-based app...

Isoforms of Hsp70-binding human LDL in adult Schistosoma mansoni worms.

Parasitol. Res. 114(3) , 1145-52, (2015)

Schistosoma mansoni is one of the most common parasites infecting humans. They are well adapted to the host, and this parasite's longevity is a consequence of effective escape from the host immune system. In the blood circulation, lipoproteins not only help t...