Estradiol Benzoate
Estradiol Benzoate structure
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Common Name | Estradiol Benzoate | ||
|---|---|---|---|---|
| CAS Number | 50-50-0 | Molecular Weight | 376.488 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 531.2±50.0 °C at 760 mmHg | |
| Molecular Formula | C25H28O3 | Melting Point | 191-198 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 212.0±22.9 °C | |
| Symbol |
GHS08 |
Signal Word | Danger | |
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Evaluation of the discriminative potential of a novel biomarker for estradiol treatments in bovine animals.
J. Agric. Food Chem. 63(1) , 370-8, (2015) The endogenous occurrence of natural hormones obstructs the application of classical targeted methods as confirmatory options. In the case of estradiol, the ultimate confirmation of its exogenous administration relies on gas chromatography coupled to combusti... |
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Localization of cytochrome P450 and related enzymes in adult rat testis and downregulation by estradiol and bisphenol A.
Toxicol. Sci. 140(1) , 26-39, (2014) There is a growing body of evidence that exposure to endocrine disrupting chemicals and to estrogenic compounds in particular can affect the testis and male fertility. In the present study, the constitutive expression of steroidogenic and non-steroidogenic cy... |
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Neonatal estrogen exposure results in biphasic age-dependent effects on the skeletal development of male mice.
Endocrinology 156(1) , 193-202, (2015) Peak bone mass, one of the most important predictors for fracture risk later in life, is attained during puberty and adolescence and influenced by neonatal and pubertal sex-specific gonadal hormones and GH-IGF-I secretion patterns. This study examined the eff... |
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Pregnancy induces resistance to the anorectic effect of hypothalamic malonyl-CoA and the thermogenic effect of hypothalamic AMPK inhibition in female rats.
Endocrinology 156(3) , 947-60, (2015) During gestation, hyperphagia is necessary to cope with the metabolic demands of embryonic development. There were three main aims of this study: Firstly, to investigate the effect of pregnancy on hypothalamic fatty acid metabolism, a key pathway for the regu... |
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Neuroestradiol in the hypothalamus contributes to the regulation of gonadotropin releasing hormone release.
J. Neurosci. 33(49) , 19051-9, (2013) Release of gonadotropin releasing hormone (GnRH) from the medial basal hypothalamus (MBH)/median eminence region (S-ME) is essential for normal reproductive function. GnRH release is profoundly regulated by the negative and positive feedback effects of ovaria... |
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Developmental exposure to estrogen alters differentiation and epigenetic programming in a human fetal prostate xenograft model.
PLoS ONE 10(3) , e0122290, (2015) Prostate cancer is the most frequent non-cutaneous malignancy in men. There is strong evidence in rodents that neonatal estrogen exposure plays a role in the development of this disease. However, there is little information regarding the effects of estrogen i... |
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Effects of the estrous cycle and ovarian hormones on central expression of interleukin-1 evoked by stress in female rats.
Neuroendocrinology 100(2-3) , 162-77, (2015) Exposure to stressors such as foot shock (FS) leads to increased expression of multiple inflammatory factors, including the proinflammatory cytokine interleukin-1 (IL-1) in the brain. Studies have indicated that there are sex differences in stress reactivity,... |
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Disruption of reproductive aging in female and male rats by gestational exposure to estrogenic endocrine disruptors.
Endocrinology 154(6) , 2129-43, (2013) Polychlorinated biphenyls (PCBs) are industrial contaminants and known endocrine-disrupting chemicals. Previous work has shown that gestational exposure to PCBs cause changes in reproductive neuroendocrine processes. Here we extended work farther down the lif... |
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Allopregnanolone's attenuation of the lordosis-inhibiting effects of restraint is blocked by the antiprogestin, CDB-4124.
Pharmacol. Biochem. Behav. 122 , 16-9, (2014) A brief restraint experience reduces lordosis behavior in ovariectomized females that have been hormonally primed with estradiol benzoate. The addition of progesterone to the priming prevents the lordosis inhibition. Based on prior studies with an inhibitor o... |
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Heterozygous deletion of ventral anterior homeobox (vax1) causes subfertility in mice.
Endocrinology 155(10) , 4043-53, (2014) The known genetic causes of idiopathic hypogonadotropic hypogonadism (IHH) are often associated with the loss of GnRH neurons, leading to the disruption of the hypothalamic pituitary gonadal axis and subfertility. The majority of IHH cases have unknown origin... |