valerylsalicylic acid
valerylsalicylic acid structure
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Common Name | valerylsalicylic acid | ||
|---|---|---|---|---|
| CAS Number | 64206-54-8 | Molecular Weight | 222.24 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 357.6±25.0 °C at 760 mmHg | |
| Molecular Formula | C12H14O4 | Melting Point | 86-87ºC(lit.) | |
| MSDS | USA | Flash Point | 135.5±16.7 °C | |
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COX-2 mediated induction of endothelium-independent contraction to bradykinin in endotoxin-treated porcine coronary artery.
J. Cardiovasc. Pharmacol. 64(3) , 209-17, (2014) This study examined the vascular effects of bradykinin in health and vascular inflammation comparing responses of isolated pig coronary arteries in the absence and presence of endotoxins. Bradykinin induced contractions in lipopolysaccharide-treated, but not ... |
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Resveratrol potently reduces prostaglandin E2 production and free radical formation in lipopolysaccharide-activated primary rat microglia.
J. Neuroinflammation 4 , 25, (2007) Neuroinflammatory responses are triggered by diverse ethiologies and can provide either beneficial or harmful results. Microglial cells are the major cell type involved in neuroinflammation, releasing several mediators, which contribute to the neuronal demise... |
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Cyclooxygenase-2 enhances alpha2beta1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells.
Mol. Cancer 9 , 43, (2010) Cyclooxygenase (COX)-2, the inducible isoform of prostaglandin (PG) synthase, has been implicated in tumor metastasis. Interaction of COX-2 with its specific EP receptors on the surface of cancer cells has been reported to induce cancer invasion. However, the... |
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Des-Arg9-bradykinin causes kinin B1 receptor mediated endothelium-independent contractions in endotoxin-treated porcine coronary arteries.
Pharmacol. Res. 90 , 18-24, (2014) This study examined responses of isolated pig coronary arteries after kinin B1 receptor induction by endotoxin. Des-Arg9-bradykinin (DBK) induced concentration-dependent, endothelium-independent contractions in lipopolysaccharide (LPS)-treated but not untreat... |
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Mechanisms Underlying Enhanced Noradrenaline-Induced Femoral Arterial Contractions of Spontaneously Hypertensive Rats: Involvement of Endothelium-Derived Factors and Cyclooxygenase-Derived Prostanoids.
Biol. Pharm. Bull. 39 , 384-93, (2016) We investigated the relationship between noradrenaline (NAd)-induced contractions, endothelial function, and hypertension in femoral arteries isolated from spontaneously hypertensive rats (SHR). In the femoral arteries of SHR, vs. age-matched control Wistar K... |