valerylsalicylic acid
valerylsalicylic acid structure
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Common Name | valerylsalicylic acid | ||
|---|---|---|---|---|
| CAS Number | 64206-54-8 | Molecular Weight | 222.24 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 357.6±25.0 °C at 760 mmHg | |
| Molecular Formula | C12H14O4 | Melting Point | 86-87ºC(lit.) | |
| MSDS | USA | Flash Point | 135.5±16.7 °C | |
Use of valerylsalicylic acidValeryl salicylate is a potent and irreversible cyclooxygenase-1 (COX-1) inhibitor. Valeryl salicylate shows anti-inflammatory effect[1]. |
| Name | valerylsalicylic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Valeryl salicylate is a potent and irreversible cyclooxygenase-1 (COX-1) inhibitor. Valeryl salicylate shows anti-inflammatory effect[1]. |
|---|---|
| Related Catalog | |
| Target |
COX-1 |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 357.6±25.0 °C at 760 mmHg |
| Melting Point | 86-87ºC(lit.) |
| Molecular Formula | C12H14O4 |
| Molecular Weight | 222.24 |
| Flash Point | 135.5±16.7 °C |
| Exact Mass | 222.089203 |
| PSA | 63.60000 |
| LogP | 2.78 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.530 |
| InChIKey | WJHZBTMHUNVIKC-UHFFFAOYSA-N |
| SMILES | CCCCC(=O)Oc1ccccc1C(=O)O |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2918990090 |
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valerylsalicyli... CAS#:64206-54-8 |
| Literature: Hofstee Journal of Biological Chemistry, 1952 , vol. 199, p. 365,366 |
| Precursor 2 | |
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| DownStream 0 | |
| HS Code | 2918990090 |
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| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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COX-2 mediated induction of endothelium-independent contraction to bradykinin in endotoxin-treated porcine coronary artery.
J. Cardiovasc. Pharmacol. 64(3) , 209-17, (2014) This study examined the vascular effects of bradykinin in health and vascular inflammation comparing responses of isolated pig coronary arteries in the absence and presence of endotoxins. Bradykinin i... |
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Resveratrol potently reduces prostaglandin E2 production and free radical formation in lipopolysaccharide-activated primary rat microglia.
J. Neuroinflammation 4 , 25, (2007) Neuroinflammatory responses are triggered by diverse ethiologies and can provide either beneficial or harmful results. Microglial cells are the major cell type involved in neuroinflammation, releasing... |
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Cyclooxygenase-2 enhances alpha2beta1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells.
Mol. Cancer 9 , 43, (2010) Cyclooxygenase (COX)-2, the inducible isoform of prostaglandin (PG) synthase, has been implicated in tumor metastasis. Interaction of COX-2 with its specific EP receptors on the surface of cancer cell... |
| valerylsalicylic acid |
| 2-Valeryloxybenzoic acid Valerylsalicylic acid vsa |
| 2-pentanoyloxybenzoic acid |
| Benzoic acid, 2-[(1-oxopentyl)oxy]- |
| 2-(Pentanoyloxy)benzoic acid |
| MFCD00041466 |