Chrysomycin A

Chrysomycin A Structure
Chrysomycin A structure
Common Name Chrysomycin A
CAS Number 82196-88-1 Molecular Weight 508.517
Density 1.4±0.1 g/cm3 Boiling Point 799.7±60.0 °C at 760 mmHg
Molecular Formula C28H28O9 Melting Point N/A
MSDS Chinese USA Flash Point 269.6±26.4 °C

Angucyclines: Biosynthesis, mode-of-action, new natural products, and synthesis.

Nat. Prod. Rep. 29(2) , 264-325, (2012)

Covering: 1997 to 2010. The angucycline group is the largest group of type II PKS-engineered natural products, rich in biological activities and chemical scaffolds. This stimulated synthetic creativity and biosynthetic inquisitiveness. The synthetic studies u...

The chemistry of the antibiotics chrysomycin A and B. Antitumor activity of chrysomycin A.

J. Antibiot. 35(9) , 1194-201, (1982)

The yellow antibiotic chrysomycin, isolated in crystalline form in 1955, is found to consist of two closely related components, a major one, chrysomycin A, and a minor one, chrysomycin B. They differ only through the replacement of a vinyl group of chrysomyci...

Antitumor activity of chrysomycins M and V.

J. Antibiot. 42(9) , 1446-8, (1989)

Activation of antitumor agent gilvocarcins by visible light.

Science 223(4631) , 69-71, (1984)

Gilvocarcins that are antitumor agents are activated by low doses of visible light to induce bacteriophage lambda in Escherichia coli. This result is dependent on interaction with DNA. Gilvocarcin M, an analog without antitumor activity, failed to induce the ...

Cloning and characterization of the ravidomycin and chrysomycin biosynthetic gene clusters.

ChemBioChem. 11(4) , 523-32, (2010)

The gene clusters responsible for the biosynthesis of two antitumor antibiotics, ravidomycin and chrysomycin, have been cloned from Streptomyces ravidus and Streptomyces albaduncus, respectively. Sequencing of the 33.28 kb DNA region of the cosmid cosRav32 an...

Studies on the mechanism of actin of gilvocarcin V and chrysomycin A.

J. Antibiot. 35(4) , 545-8, (1982)