H-Cys(Acm)-OH HCl

H-Cys(Acm)-OH HCl Structure
H-Cys(Acm)-OH HCl structure
Common Name H-Cys(Acm)-OH HCl
CAS Number 28798-28-9 Molecular Weight 228.69700
Density 1.315g/cm3 Boiling Point 456.5ºC at 760mmHg
Molecular Formula C6H13ClN2O3S Melting Point -165ºC (dec.)
MSDS USA Flash Point 229.9ºC

Side reaction during the deprotection of (S-acetamidomethyl)cysteine in a peptide with a high serine and threonine content.

Int. J. Pept. Protein Res. 41(1) , 85-95, (1993)

The acetamidomethyl (Acm) group is a widely used protecting group for the thiol of cysteine during the SPPS process. We prepared the amino terminal loop of the snake alpha-neurotoxin, [Cys3,Cys23, Ser17](1-24) amide, from the linear peptide [Cys(Acm)3,23,Ser1...

Acetamidomethyl. A novel thiol protecting group for cysteine.

J. Am. Chem. Soc. 94 , 5456, (1972)

Studies on a growth-inhibitory peptide derived from alpha-fetoprotein and some analogs.

J. Pept. Res. 57(1) , 29-38, (2001)

A 34-amino acid synthetic peptide was derived from the third domain of human alpha-fetoprotein, and the peptide was shown to inhibit estrogen-stimulated growth. Under certain conditions, however, the peptide lost growth-inhibitory activity. A biophysical stud...

Side reaction of S-to-N acetamidomethyl shift during disulfide bond formation by iodine oxidation of S-acetamidomethyl-cysteine in a glutamine-containing peptide.

Pept. Res. 8(6) , 316-20, (1995)

During the time course of disulfide bond formation by iodine oxidation (in a methanolic and hydrochloric acid solution) of a cysteinyl(S-acetamidomethyl)-glutaminyl tridecapeptide, we observed by ESI, FAB mass spectrometry (pseudo-molecular ion and ion-fragme...

[Direct transition of S-acetamidomethyl-protected peptide 593-603 of HIV-2 gp41 into a cyclic disulfide using iodine. Study of side reactions].

Bioorg. Khim. 22(5) , 370-5, (1996)

Removal of Acm-protecting group from thiol functional groups of Cys residues with simultaneous disulfide bridge formation by iodine in acetic acid was studied in the course of the synthesis of a peptide fragment corresponding to 593-603 sequence of HIV-2 gp41...

Deprotection of S-acetamidomethyl cysteine-containing peptides by silver trifluoromethanesulfonate avoids the oxidation of methionines.

Anal. Biochem. 228(1) , 173-7, (1995)

J. Diaz et al.

Bioorg. Chem. 8 , 429, (1979)

B. Kamber et al.

Helv. Chim. Acta 63 , 899, (1980)