N-p-Tosylazetidine

N-p-Tosylazetidine Structure
N-p-Tosylazetidine structure
Common Name N-p-Tosylazetidine
CAS Number 7730-45-2 Molecular Weight 211.281
Density 1.3±0.1 g/cm3 Boiling Point 337.6±35.0 °C at 760 mmHg
Molecular Formula C10H13NO2S Melting Point 119-122ºC(lit.)
MSDS USA Flash Point 158.0±25.9 °C

Ag(I)-catalyzed regioselective ring-opening of N-tosylaziridine and N-tosylazetidine with S-, O-, and N-nucleophiles and tethered dinucleophiles.

J. Org. Chem. 76(5) , 1475-8, (2011)

[Ag(COD)(2)]PF(6) catalyzes the ring-opening of N-tosylaziridines and -azetidines with alcohols, amines, thiols, and related tethered 1,2-ethane dinucleophiles. Initial rate studies and DFT-based evaluation of stepwise energetics suggest an inverse relationsh...