Galanin (1-13)-Substance P (5-11) amide

Galanin (1-13)-Substance P (5-11) amide Structure
Galanin (1-13)-Substance P (5-11) amide structure
Common Name Galanin (1-13)-Substance P (5-11) amide
CAS Number 138579-66-5 Molecular Weight 2199.53000
Density N/A Boiling Point N/A
Molecular Formula C104H151N25O26S Melting Point N/A
MSDS Chinese USA Flash Point N/A

The GTP- and Phospholipid-Binding Protein TTD14 Regulates Trafficking of the TRPL Ion Channel in Drosophila Photoreceptor Cells.

PLoS Genet. 11(10) , e1005578, (2015)

Recycling of signaling proteins is a common phenomenon in diverse signaling pathways. In photoreceptors of Drosophila, light absorption by rhodopsin triggers a phospholipase Cβ-mediated opening of the ion channels transient receptor potential (TRP) and TRP-li...

Modulation of the mitochondrial voltage dependent anion channel (VDAC) by curcumin.

Biochim. Biophys. Acta 1848(1 Pt A) , 151-8, (2015)

Voltage dependent anion channel (VDAC) of mitochondria plays a crucial role in apoptosis. Human VDAC-1, reconstituted in planar lipid bilayer showed reduced conductance when treated with curcumin. Curcumin interacts with residues in the α helical N-terminus o...

A crayfish molar tooth protein with putative mineralized exoskeletal chitinous matrix properties.

J. Exp. Biol. 218 , 3487-98, (2015)

Some crustaceans possess exoskeletons that are reinforced with calcium carbonate. In the crayfish Cherax quadricarinatus, the molar tooth, which is part of the mandibular exoskeleton, contains an unusual crystalline enamel-like apatite layer. As this layer re...

Three New Cutinases from the Yeast Arxula adeninivorans That Are Suitable for Biotechnological Applications.

Appl. Environ. Microbiol. 81 , 5497-510, (2015)

The genes ACUT1, ACUT2, and ACUT3, encoding cutinases, were selected from the genomic DNA of Arxula adeninivorans LS3. The alignment of the amino acid sequences of these cutinases with those of other cutinases or cutinase-like enzymes from different fungi sho...

Malonate-based inhibitors of mammalian serine racemase: kinetic characterization and structure-based computational study.

Eur. J. Med. Chem. 89 , 189-97, (2014)

Overactivation of NMDA receptors has been implicated in various neuropathological conditions, including brain ischaemia, neurodegenerative disorders and epilepsy. Production of d-serine, an NMDA receptor co-agonist, from l-serine is catalyzed in vivo by the p...

The Polymerization of Aeromonas hydrophila AH-3 O-Antigen LPS: Concerted Action of WecP and Wzy.

PLoS ONE 10 , e0131905, (2015)

The repeat units of heteropolymeric O antigen are synthesized at the cytosolic side of the inner bacterial membrane via the Wzx/Wzy-dependent assembly pathway. After being translocated across the membrane by Wzx, each repeat unit is polymerized by Wzy to form...

A prime/boost strategy using DNA/fowlpox recombinants expressing the genetically attenuated E6 protein as a putative vaccine against HPV-16-associated cancers.

J. Transl. Med. 13 , 80, (2015)

Considering the high number of new cases of cervical cancer each year that are caused by human papilloma viruses (HPVs), the development of an effective vaccine for prevention and therapy of HPV-associated cancers, and in particular against the high-risk HPV-...

Antibodies against hemolysin and cytotoxic necrotizing factor type 1 (CNF1) reduce bladder inflammation in a mouse model of urinary tract infection with toxigenic uropathogenic Escherichia coli.

Infect. Immun. 83(4) , 1661-73, (2015)

Uropathogenic Escherichia coli (UPEC) is the leading cause of cystitis. Cytotoxic necrotizing factor 1 (CNF1) and hemolysin (Hly) are toxins made by approximately 50% of UPEC isolates. CNF1 and Hly contribute to the robust inflammatory response in the bladder...

Molecular and biochemical characterization of recombinant guinea pig tumor necrosis factor-alpha.

Mediators Inflamm. 2015 , 619480, (2015)

Tumor necrosis factor alpha (TNF-α) is a cytokine which plays opposing roles in the context of infectious disease pathogenesis. TNF-α is essential for the development of a protective immune response to some pathogens, for example, Mycobacterium tuberculosis, ...

Targeted delivery of CXCR4-siRNA by scFv for HER2(+) breast cancer therapy.

Biomaterials 59 , 77-87, (2015)

Therapeutics based on short interfering RNAs (siRNAs) have great potential to treat human diseases. However, the clinical application of siRNAs has been limited by their poor intracellular uptake, low serum stability, and inability to target specific cells. I...