Dihydrofluorescein diacetate
Dihydrofluorescein diacetate structure
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Common Name | Dihydrofluorescein diacetate | ||
|---|---|---|---|---|
| CAS Number | 35340-49-9 | Molecular Weight | 418.39600 | |
| Density | 1.353g/cm3 | Boiling Point | 554.3ºC at 760 mmHg | |
| Molecular Formula | C24H18O7 | Melting Point | 213-215ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
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M2 Polarization of Monocytes-Macrophages Is a Hallmark of Indian Post Kala-Azar Dermal Leishmaniasis.
PLoS Negl. Trop. Dis. 9 , e0004145, (2015) The high level of functional diversity and plasticity in monocytes/macrophages has been defined within in vitro systems as M1 (classically activated), M2 (alternatively activated) and deactivated macrophages, of which the latter two subtypes are associated wi... |
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Extensive crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in human lymphoma cells.
MAbs 7(1) , 199-211, (2015) Epratuzumab has demonstrated therapeutic activity in patients with non-Hodgkin lymphoma, acute lymphoblastic leukemia, systemic lupus erythematosus, and Sjögren's syndrome, but its mechanism of affecting normal and malignant B cells remains incompletely under... |
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Po2 cycling protects diaphragm function during reoxygenation via ROS, Akt, ERK, and mitochondrial channels.
Am. J. Physiol. Cell Physiol. 309 , C759-66, (2015) Po2 cycling, often referred to as intermittent hypoxia, involves exposing tissues to brief cycles of low oxygen environments immediately followed by hyperoxic conditions. After experiencing long-term hypoxia, muscle can be damaged during the subsequent reintr... |
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Heritable transmission of stress resistance by high dietary glucose in Caenorhabditis elegans.
PLoS Genet. 10(5) , e1004346, (2014) Glucose is a major energy source and is a key regulator of metabolism but excessive dietary glucose is linked to several disorders including type 2 diabetes, obesity and cardiac dysfunction. Dietary intake greatly influences organismal survival but whether th... |
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Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio.
PLoS ONE 7(7) , e42117, (2012) The DNA/RNA-binding proteins TDP-43 and FUS are found in protein aggregates in a growing number of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and related dementia, but little is known about the neurotoxic mechanisms. We have gen... |
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Mimicking the phosphorylation of Rsp5 in PKA site T761 affects its function and cellular localization.
Eur. J. Cell Biol. 94 , 576-88, (2015) Rsp5 ubiquitin ligase belongs to the Nedd4 family of proteins, which affect a wide variety of processes in the cell. Here we document that Rsp5 shows several phosphorylated variants of different mobility and the migration of the phosphorylated forms of Rsp5 w... |
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Higenamine Combined with [6]-Gingerol Suppresses Doxorubicin-Triggered Oxidative Stress and Apoptosis in Cardiomyocytes via Upregulation of PI3K/Akt Pathway.
Evid. Based. Complement. Alternat. Med. 2013 , 970490, (2013) Sini decoction is a well-known formula of traditional Chinese medicine, which has been used to treat cardiovascular disease for many years. Previously, we demonstrated that Sini decoction prevented doxorubicin-induced heart failure in vivo. However, its activ... |
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TDP-1/TDP-43 regulates stress signaling and age-dependent proteotoxicity in Caenorhabditis elegans.
PLoS Genet. 8 , e1002806, (2012) TDP-43 is a multifunctional nucleic acid binding protein linked to several neurodegenerative diseases including Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia. To learn more about the normal biological and abnormal pathological role of this p... |
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A permeable cuticle is associated with the release of reactive oxygen species and induction of innate immunity.
PLoS Pathog. 7 , e1002148, (2011) Wounded leaves of Arabidopsis thaliana show transient immunity to Botrytis cinerea, the causal agent of grey mould. Using a fluorescent probe, histological staining and a luminol assay, we now show that reactive oxygen species (ROS), including H(2)O(2) and O(... |
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Perception of soft mechanical stress in Arabidopsis leaves activates disease resistance.
BMC Plant Biol. 13 , 133, (2013) In a previous study we have shown that wounding of Arabidopsis thaliana leaves induces a strong and transient immunity to Botrytis cinerea, the causal agent of grey mould. Reactive oxygen species (ROS) are formed within minutes after wounding and are required... |