2,3,5,6-tetrafluorothiophenol

2,3,5,6-tetrafluorothiophenol Structure
2,3,5,6-tetrafluorothiophenol structure
Common Name 2,3,5,6-tetrafluorothiophenol
CAS Number 769-40-4 Molecular Weight 182.13900
Density 1.53 Boiling Point 152-153 °C(lit.)
Molecular Formula C6H2F4S Melting Point N/A
MSDS Chinese USA Flash Point 119 °F
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning

A gas-chromatographic assay method for busulfan with sensitivity for test dose therapeutic monitoring.

J. Pharm. Biomed. Anal. 13(9) , 1073-8, (1995)

A gas-chromatographic assay method was developed and validated for determination of busulfan in human plasma for test dose therapeutic drug monitoring. Busulfan and the internal standard (1,6-bis-(methanesulfonyloxy)hexane) were extracted from plasma samples ...

Gas-chromatographic analysis of busulfan for therapeutic drug monitoring.

Cancer Chemother. Pharmacol. 32(2) , 137-42, (1993)

The development and validation of a gas chromatographic assay method for determination of total and free busulfan concentrations in human plasma for pharmacokinetic studies is reported. 1,6-Bis(methanesulfonyloxy)hexane, the internal standard, and a potential...

Quantification of busulfan in plasma by gas chromatography-mass spectrometry following derivatization with tetrafluorothiophenol.

J. Chromatogr. B. Biomed. Sci. Appl. 709(1) , 47-56, (1998)

A specific and highly sensitive method has been developed for the determination of busulfan in plasma by gas chromatography-mass spectrometry using a deuterium-labeled busulfan (busulfan-d8) as internal standard. Plasma containing busulfan and busulfan-d8 wer...

High-performance liquid chromatographic method for quantification of busulfan in plasma after derivatization by tetrafluorothiophenol.

J. Chromatogr. B. Biomed. Sci. Appl. 721(1) , 147-52, (1999)

A high-performance liquid chromatographic (HPLC) method was developed and validated for the determination of busulfan in plasma. Busulfan was extracted in toluene, derivatized by 2,3,5,6-tetrafluorothiophenol to obtain di-TFTP-butane, the derivatization produ...