H-His-Leu-OH
H-His-Leu-OH structure
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Common Name | H-His-Leu-OH | ||
|---|---|---|---|---|
| CAS Number | 7763-65-7 | Molecular Weight | 268.31200 | |
| Density | 1.249g/cm3 | Boiling Point | 623ºC at 760 mmHg | |
| Molecular Formula | C12H20N4O3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 330.6ºC | |
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Sinapic acid prevents hypertension and cardiovascular remodeling in pharmacological model of nitric oxide inhibited rats.
PLoS ONE 9(12) , e115682, (2014) Hypertensive heart disease is a constellation of abnormalities that includes cardiac fibrosis in response to elevated blood pressure, systolic and diastolic dysfunction. The present study was undertaken to examine the effect of sinapic acid on high blood pres... |
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Characterization of the intrarenal renin-angiotensin system in experimental alport syndrome.
Am. J. Pathol. 185 , 1423-35, (2015) Blockade of the renin-angiotensin system attenuates the progression of experimental and clinical Alport syndrome (AS); however, the underlying mechanism(s) remains largely unknown. We evaluated the renin-angiotensin system in 4- and 7-week-old homozygous for ... |
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Ternary nickel(II) complexes as hydrolytic DNA-cleavage agents.
Chem. Biodivers. 3 , 231-244, (2006) A series of small model complexes made from Ni(II) and the ligands ethylenediamine (en), histamine (hist), and histidylleucine (HisLeu) were prepared and studied as potential hydrolytic DNA-cleavage agents. The stability constants and species-distribution cur... |
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Ternary zinc(II)-dipeptide complexes for the hydrolytic cleavage of DNA at physiological pH.
Chem. Biodivers. 2 , 672-683, (2005) A series of Zn(II) complexes with cysteinylglycine (CysGly) and histidylserine (HisSer), and of CysGly and histidylphenylalanine (HisPhe) were investigated. Complex stabilities were determined potentiometrically, and binding geometries were probed by means of... |
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L-histidyl-L-serine 3.7-hydrate: water channels in the crystal structure of a polar dipeptide.
Acta Crystallogr. C 66 , o531-534, (2010) Dipeptides may form nanotubular structures with pore diameters in the range 3.2-10 Å. These compounds normally contain at least one and usually two hydrophobic residues, but L-His-L-Ser hydrate, C(9)H(14)N(4)O(4)·3.7H(2)O, with two hydrophilic residues, forms... |
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Novel peptide-based copper(II) complexes for total hydrolytic cleavage of DNA.
Chem. Biodivers. 2 , 1338-1350, (2005) Stable Cu(II) complexes with histamine- and histidine-containing dipeptides histidylserine and histidylphenylalanine have been developed. Their interaction in solution has been investigated, and the stability of their complexes was determined. The nature of b... |
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Copper(II) complexes containing N,N-donor ligands and dipeptides act as hydrolytic DNA-cleavage agents.
Chem. Biodivers. 1 , 839-853, (2004) Copper(II) complexes are known to play a significant role in both naturally occurring biological systems and pharmaceutical agents. Recently, Cu(II) complexes have gained importance in DNA cleavage essential for the development of anticancer drugs and chemoth... |
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Effect of vasoactive intestinal peptide, peptide histidine isoleucine and growth hormone-releasing factor-40 on bombesin-like immunoreactivity, somatostatin and gastrin release from the perfused rat stomach.
Peptides 7(1) , 127-33, (1986) Bombesin-like immunoreactivity (BLI) has been demonstrated in neurons of the gastrointestinal tract and gastric BLI secretion can be demonstrated in response to the classical neurotransmitter acetylcholine. Since structurally related peptides VIP, PHI and GRF... |
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Molecular structures of L-Leu-L-Tyr, Gly-D,L-Met.p-toluenesulfonate and L-His-L-Leu.
Acta Crystallogr. B 49 ( Pt 1) , 123-30, (1993) L-Leu-L-Tyr, (I), C15H22N2O4, M(r) = 294.35, crystallizes from MeOH/5% dimethyl sulfoxide in the orthorhombic space group P2(1)2(1)2(1). a = 5.644 (1), b = 12.094 (3), c = 22.548 (4) A, V = 1539.0 (5) A3, Z = 4, Dx = 1.270 g cm-3, Cu K alpha, lambda = 1.54184... |
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Identification of enzymatically produced peptide fragments by liquid chromatography and mass spectrometry.
Anal. Biochem. 121(1) , 97-102, (1982) The qualitative and quantitative determination of peptide fragments of angiotensin I generated by rat lung dipeptidyl carboxypeptidase (angiotensin converting enzyme, EC 3.4.15.1) is described. Enzymatically formed peptide fragments, after derivatization with... |