GNF-2
GNF-2 structure
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Common Name | GNF-2 | ||
|---|---|---|---|---|
| CAS Number | 778270-11-4 | Molecular Weight | 374.317 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 536.4±50.0 °C at 760 mmHg | |
| Molecular Formula | C18H13F3N4O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 278.2±30.1 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Allosteric inhibitors of Bcr-abl-dependent cell proliferation.
Nat. Chem. Biol. 2 , 95-102, (2006) Chronic myelogenous leukemia (CML) is a myeloproliferative disorder characterized at the molecular level by the expression of Bcr-abl, a 210-kDa fusion protein with deregulated tyrosine kinase activity. Encouraged by the clinical validation of Bcr-abl as the ... |
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Inhibitors of Bcr-abl... breaking new ground again.
Nat. Chem. Biol. 2nd ed.,, 63-64, (2006)
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