PACOCF3

PACOCF3 Structure
PACOCF3 structure
Common Name PACOCF3
CAS Number 141022-99-3 Molecular Weight 308.423
Density 1.0±0.1 g/cm3 Boiling Point 329.0±37.0 °C at 760 mmHg
Molecular Formula C17H31F3O Melting Point N/A
MSDS Chinese USA Flash Point 227.1±18.0 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

Inhibition of macrophage Ca(2+)-independent phospholipase A2 by bromoenol lactone and trifluoromethyl ketones.

J. Biol. Chem. 270 , 445, (1995)

A novel Ca(2+)-independent phospholipase A2 (PLA2) has recently been purified from the murine macrophage-like cell line P388D1 (Ackermann, E. J., Kempner, E. S., and Dennis, E. A. (1994) J. Biol. Chem. 269, 9227-9233). This enzyme is now shown to be inhibited...

Irreversible inhibition of Ca(2+)-independent phospholipase A2 by methyl arachidonyl fluorophosphonate.

Biochim. Biophys. Acta 1302 , 55-60, (1996)

Methyl arachidonyl fluorophosphonate (MAFP) has been recently reported to be a selective, active-site directed, irreversible inhibitor of the Group IV 85 kDa cytosolic phospholipase A2 (cPLA2). We have now shown that this compound also potently inhibits the C...

Metabolic oxidation regulates embryonic stem cell differentiation.

Nat. Chem. Biol. 6 , 411-7, (2010)

Metabolites offer an important unexplored complementary approach to understanding the pluripotency of stem cells. Using MS-based metabolomics, we show that embryonic stem cells are characterized by abundant metabolites with highly unsaturated structures whose...

Dual action of palmitoyl trifluoromethyl ketone (PACOCF3) on Ca2+ signaling: activation of extracellular Ca2+ influx and alteration of ATP- and bradykinin-induced Ca2+ responses in Madin Darby canine kidney cells Jan, C.R., et al.

Toxicology 74 , 447-451, (2000)