Octanoic acid,1,1'-(1,2-ethanediyl) ester

Octanoic acid,1,1'-(1,2-ethanediyl) ester Structure
Octanoic acid,1,1'-(1,2-ethanediyl) ester structure
Common Name Octanoic acid,1,1'-(1,2-ethanediyl) ester
CAS Number 627-86-1 Molecular Weight 314.46000
Density 0.945g/cm3 Boiling Point 387.1ºC at 760 mmHg
Molecular Formula C18H34O4 Melting Point N/A
MSDS Chinese USA Flash Point 179.8ºC

Attenuation of sn-1,2-diacylglycerol second messengers by diacylglycerol kinase. Inhibition by diacylglycerol analogs in vitro and in human platelets.

J. Biol. Chem. 261 , 6993, (1986)

Diacylglycerol kinase is though to play a central role in the metabolism of diacylglycerol second messengers in agonist-stimulated cells. A series of diacylglycerol analogs were tested for their ability to act as substrates or inhibitors of diacylglycerol kin...

Peroxides of vanadate induce activation of phospholipase D in HL-60 cells. Role of tyrosine phosphorylation.

J. Biol. Chem. 267(17) , 11908-16, (1992)

To determine the role of protein tyrosine phosphorylation in the activation of phospholipase D (PLD), electropermeabilized HL-60 cells labeled in [3H]alkyl-phosphatidylcholine were treated with vanadate derivatives. Micromolar concentrations of vanadyl hydrop...

Phosphocholine transferase is more efficient than diacylglycerol kinase as possible attenuator of diacylglycerol signals in primordial human placenta.

Acta Physiol. Hung. 81(4) , 341-54, (1993)

Diacylglycerols (DAG) are assumed to play intracellular signal roles in rapidly growing tissues like those present in the primordial human placenta. The aim of the present study was to gain information on the capacity of DAG-kinase and CDP-choline: DAG phosph...

Diacylglycerol kinase inhibitors R59022 and dioctanoylethylene glycol potentiate the respiratory burst of neutrophils by raising cytosolic Ca2+.

Biochem. Biophys. Res. Commun. 161(1) , 95-100, (1989)

The diacylglycerol kinase inhibitors, R59022 and dioctanoylethylene glycol (diC8-eg), potentiate stimulation of the respiratory burst by the chemotactic tripeptide N-formyl-methionyl-leucyl-phenylalanine (fMLP) in human neutrophils. However, in contrast to th...

Attenuation of diacylglycerol signal in the primordial human placenta: role of phosphatidylcholine formation.

Biochim. Biophys. Acta 1210(1) , 105-12, (1993)

Metabolic conversion of the synthetic DAG, dioctanoylglycerol (DOCG) into the dioctanoyl species of phosphatidic acid (PADOCG) and phosphatidylcholine (PCDOCG) in minced human primordial placenta incubated with [32P]phosphate was studied. Time-course experime...

Diol lipids are activators of protein kinase C.

FEBS Lett. 232(2) , 286-8, (1988)

Diol lipids (dioleoyl- and dioctanoylethylene glycol) at relatively low concentrations (approximately 10 microM) were found to activate significantly protein kinase C in the presence of phosphatidylserine or phosphatidylinositol. Since diol lipids are widespr...