1-(2-Methoxyphenyl)piperazine
1-(2-Methoxyphenyl)piperazine structure
|
Common Name | 1-(2-Methoxyphenyl)piperazine | ||
|---|---|---|---|---|
| CAS Number | 35386-24-4 | Molecular Weight | 192.258 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 379.9±0.0 °C at 760 mmHg | |
| Molecular Formula | C11H16N2O | Melting Point | 35-40 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 154.0±23.7 °C | |
| Symbol |
GHS05 |
Signal Word | Danger | |
|
Development of a novel derivatization reagent for the sampling and analysis of total isocyanate group in air and comparison of its performance with that of several established reagents.
Am. Ind. Hyg. Assoc. J. 57(10) , 905-13, (1996) Analytical reference standards generally are not available for non-monomeric isocyanate species, making accurate identification and quantitation by high-performance liquid chromatography (HPLC) difficult. A successful derivatizing reagent must react rapidly w... |
|
|
Comparison of hollow fiber liquid-phase microextraction and ultrasound-assisted low-density solvent dispersive liquid-liquid microextraction for the determination of drugs of abuse in biological samples by gas chromatography-mass spectrometry.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 989 , 46-53, (2015) Two microextraction techniques based on hollow fiber liquid-phase microextraction (HF-LPME) and ultrasound-assisted low-density solvent dispersive liquid-liquid microextraction (UA-LDS-DLLME) had been applied for the determination of drugs of abuse (methamphe... |
|
|
Preparation and biodistribution of 1-((2-methoxyphenyl) piperazine)ferrocenecarboxamide labeled with technetium-99m as a potential brain receptor imaging agent.
Eur. J. Med. Chem. 97 , 280-8, (2015) The goal of this study is to develop a novel brain receptor imaging agent. This study reports the synthesis, characterization and the biological evaluation of 1-((2-methoxyphenyl) piperazine)ferrocenecarboxamide labeled with technetium-99 m ((99m)Tc-MP). The ... |
|
|
Role of dermal exposure in systemic intake of methylenediphenyl diisocyanate (MDI) among construction and boat building workers.
Toxicol. Lett. 232(3) , 595-600, (2015) The causal relationship between inhalation exposure to methylenediphenyl diisocyanate (MDI) and the risk of occupational asthma is well known, but the role of dermal exposure and dermal uptake of MDI in this process is still unclear. The aims of this study we... |
|
|
Validation of a diffusive sampling method for airborne low-molecular isocyanates using 4-nitro-7-piperazinobenzo-2-oxa-1,3-diazole-impregnated filters and liquid chromatography-tandem mass spectrometry.
J. Chromatogr. A. 1134(1-2) , 112-21, (2006) A diffusive sampling method for the determination of low-molecular isocyanates as their 4-nitro-7-piperazinobenzo-2-oxa-1,3-diazole (NBDPZ) derivatives using tandem mass spectrometry (MS/MS) after atmospheric pressure chemical ionisation (APCI) is presented. ... |
|
|
Determination of isocyanates in air using 1-(2-methoxyphenyl)piperazine-impregnated filters: long-term sampling performance and field comparison with impingers with dibutylamine.
Ann. Occup. Hyg. 48(5) , 415-24, (2004) Isocyanates may be harmful to workers and methods for monitoring air exposure in the field are necessary. The main aim of this study was to study the field performance of a method using 1-(2-methoxyphenyl)piperazine (2MP)-impregnated filters, by side-by-side ... |
|
|
1-(o-Methoxyphenyl)piperazine is a metabolite of drugs bearing a methoxyphenylpiperazine side-chain.
J. Pharm. Pharmacol. 39(4) , 312-3, (1987) Drugs bearing an o-methoxyphenylpiperazine (oOCH3PP) moiety in the side-chain of their molecule may form oOCH3PP during biotransformation in-vivo in the rat. This has been verified by combined gas chromatography-mass spectrometry of urine from rats given oral... |
|
|
New imide 5-HT1A receptor ligands - modification of terminal fragment geometry.
Molecules 9(3) , 170-7, (2004) Two sets of new o-methoxyphenylpiperazine (MPP; series a) and 1,2,3,4-tetrahydroisoquinoline (THIQ; series b) derivatives, containing various imide moieties derived from NAN190, were synthesized and evaluated in vitro for their ability to bind to the serotoni... |
|
|
Characterisation of derivatised monomeric and prepolymeric isocyanates by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry and structural elucidation by tandem mass spectrometry.
Eur. J. Mass Spectrom. (Chichester, Eng.) 11(6) , 565-74, (2005) Isocyanates are an important class of compounds in occupational hygiene monitoring due mainly to their behaviour as respiratory sensitisers. Here, we demonstrate the application of matrix-assisted laser desorption/ionisation mass spectrometry (MALDI-MS) and M... |
|
|
[Potential cardiotonics. 5. Preparation and properties of 6-unsubstituted and 6-methyl-substituted 3-cyan-5-(pyrid-4-yl)pyridine].
Pharmazie 44(9) , 643-4, (1989)
|