(±)-Molindone Hydrochloride
(±)-Molindone Hydrochloride structure
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Common Name | (±)-Molindone Hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 15622-65-8 | Molecular Weight | 312.835 | |
| Density | N/A | Boiling Point | 462.9ºC at 760mmHg | |
| Molecular Formula | C16H25ClN2O2 | Melting Point | 180-181ºC | |
| MSDS | Chinese USA | Flash Point | 233.7ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Determination of molindone enantiomers in human plasma by high-performance liquid chromatography-tandem mass spectrometry using macrocyclic antibiotic chiral stationary phases.
J. Chromatogr. A. 1192(2) , 230-8, (2008) A sensitive and selective bioanalytical assay was developed and validated for the determination of enantiomeric molindone in human plasma using high-performance liquid chromatography-tandem mass spectrometry along with supported liquid extraction procedures. ... |
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D-cycloserine adjuvant therapy to molindone in the treatment of schizophrenia.
Clin. Neuropharmacol. 19(5) , 444-50, (1996) This preliminary investigation examined the therapeutic efficacy of two doses of oral D-cycloserine (5 and 15 mg p.o. b.i.d.) administered as an adjuvant to molindone (150 mg p.o. q.d.) in the treatment of schizophrenia. D-Cycloserine is an agonist at the N-m... |
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A phase 2a randomized, parallel group, dose-ranging study of molindone in children with attention-deficit/hyperactivity disorder and persistent, serious conduct problems.
J. Child Adolesc. Psychopharmacol. 22(2) , 102-11, (2012) To evaluate safety and tolerability of four doses of immediate-release molindone hydrochloride in children with attention-deficit/hyperactivity disorder (ADHD) and serious conduct problems.This open-label, parallel-group, dose-ranging, multicenter trial rando... |
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Famotidine adjunctive pharmacotherapy of schizophrenia: a case report.
Clin. Neuropharmacol. 18(4) , 369-74, (1995) Recent reports suggest some utility for famotidine, a histamine type 2 (H2) antagonist, in the treatment of schizophrenia. The current report describes a treatment-resistant patient with chronic undifferentiated schizophrenia whose most dramatic symptomatic i... |
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Tissue distribution of molidone in a multidrug overdose.
J. Anal. Toxicol. 28(6) , 533-6, (2004) Molindone hydrochloride (Moban) is a dihydroindolone compound dissimilar in structure to other antipsychotic drugs (i.e., phenothiazines, butyrophenones, dibenzepines, and thioxanthenes). The antipsychotic (or neuroleptic) activity of molindone makes it parti... |
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Unilateral auditory hallucinations in a boy with ipsilateral conductive hearing loss.
J. Neurol. Neurosurg. Psychiatr. 62(3) , 302, (1997)
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Could repetitive transcranial magnetic stimulation improve neurocognition in early-onset schizophrenia spectrum disorders?
J. Am. Acad. Child Adolesc. Psychiatry 51(9) , 949-51, (2012)
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The voices go, but the song remains the same: how can we rescue cognition in early-onset schizophrenia?
J. Am. Acad. Child Adolesc. Psychiatry 51(5) , 464-6, (2012)
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Treatment of morbidly obese psychotic patients with molindone: three case reports.
J. Clin. Psychiatry 70(11) , 1606-7, (2009)
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Potential lower efficacy of molindone among first-generation antipsychotics.
Am. J. Psychiatry 166(4) , 491; author reply 492-3, (2009)
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