Z-LYS-SBZL HCL

Z-LYS-SBZL HCL Structure
Z-LYS-SBZL HCL structure
Common Name Z-LYS-SBZL HCL
CAS Number 69861-89-8 Molecular Weight 422.96900
Density N/A Boiling Point 566.3ºC at 760 mmHg
Molecular Formula C21H27ClN2O3S Melting Point N/A
MSDS Chinese USA Flash Point 296.3ºC

Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors.

Biochim. Biophys. Acta 1477 , 307-323, (2000)

Natural killer (NK) and cytotoxic T-lymphocytes (CTLs) kill cells within an organism to defend it against viral infections and the growth of tumors. One mechanism of killing involves exocytosis of lymphocyte granules which causes pores to form in the membrane...

2-chloroadenosine stimulates granule exocytosis from mouse natural killer cells: evidence for signal transduction through a novel extracellular receptor.

Exp. Cell Res. 233 , 187-197, (1997)

The effect of 2-chloroadenosine (2CA), an adenosine receptor agonist, on the activation status of mouse natural killer (NK) cells was determined. Splenic lymphocytes incubated with 2CA exocytosed an NK cell-associated granzyme with N alpha-CBZ-L-lysine thiobe...

Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse.

PLoS Biol. 9 , e1001151, (2011)

Accumulation of filamentous actin (F-actin) at the immunological synapse (IS) is a prerequisite for the cytotoxic function of natural killer (NK) cells. Subsequent to reorganization of the actin network, lytic granules polarize to the IS where their contents ...

Antioxidants, Enzyme Inhibitors, and Biogenic Compounds in Grain Extracts of Barleys.

Chem. Biodivers. 12 , 1678-95, (2015)

The content of biogenic compounds and the biological activities of barley (Hordeum vulgare L.)-grain extracts was evaluated. The sufficiently large and heterogeneous set of barley genotypes (100 accessions) enabled the selection of special genotypes interesti...

The major component of Na-CBZ-L-lysine thiobenzyl ester (BLT)-specific proteases in cytoplasmic granules of murine intraepithelial lymphocytes is granzyme A. Kato Y, Yokochi T, Sasaki K, et al.

Immunobiol. 196 , 465-474, (1997)