Naphthalene-2-sulfonyl chloride

Naphthalene-2-sulfonyl chloride Structure
Naphthalene-2-sulfonyl chloride structure
Common Name Naphthalene-2-sulfonyl chloride
CAS Number 93-11-8 Molecular Weight 226.679
Density 1.4±0.1 g/cm3 Boiling Point 371.3±11.0 °C at 760 mmHg
Molecular Formula C10H7ClO2S Melting Point 74-76 °C(lit.)
MSDS Chinese USA Flash Point 178.4±19.3 °C
Symbol GHS05
GHS05
Signal Word Danger

Derivatization of primary amines by 2-naphthalenesulfonyl chloride for high-performance liquid chromatographic assay of neomycin sulfate.

J. Chromatogr. A. 369(1) , 105-15, (1986)

A normal phase high-performance liquid chromatographic (HPLC) method has been developed for the assay of neomycin sulfate. The method involves pre-column derivatization with 2-naphthalenesulfonyl chloride (NSCl) followed by extraction in chloroform and chroma...

From histamine to imidazolylalkyl-sulfonamides: the design of a novel series of histamine H3-receptor antagonists.

Bioorg. Med. Chem. Lett. 9(13) , 1825-30, (1999)

Histamine was converted to a selective histamine H3-receptor antagonist by capping the primary amine with 2-naphthalenesulfonyl chloride. Higher receptor affinity and lower variability in the data from the various bioassays were achieved with the 2-naphthalen...

Derivatization of secondary amines with 2-naphthalene-sulfonyl chloride for high-performance liquid chromatographic analysis of spectinomycin.

J. Chromatogr. A. 333(2) , 365-80, (1985)

A normal-phase high-performance liquid chromatographic (HPLC) method has been developed for the assay of spectinomycin hydrochloride and spectinomycin sulfate for detection at 254 nm. The method involves pre-column derivatization of secondary amines of specti...