1,4-Phenylenedimethanamine

1,4-Phenylenedimethanamine Structure
1,4-Phenylenedimethanamine structure
Common Name 1,4-Phenylenedimethanamine
CAS Number 539-48-0 Molecular Weight 136.194
Density 1.1±0.1 g/cm3 Boiling Point 261.9±20.0 °C at 760 mmHg
Molecular Formula C8H12N2 Melting Point 60-63 °C(lit.)
MSDS Chinese USA Flash Point 131.8±21.3 °C
Symbol GHS05
GHS05
Signal Word Danger

Synthesis and antioxidant properties of dendritic polyphenols.

Bioorg. Med. Chem. Lett. 19 , 6326-30, (2009)

Three dendritic polyphenols (generation 1) were synthesized: a syringaldehyde-based dendrimer (1), a vanillin-based dendrimer (2), and an iodinated vanillin-based dendrimer (3). They all showed strong antioxidant activity according to the 1,1-diphenyl-2-picry...

New efficient substrates for semicarbazide-sensitive amine oxidase/VAP-1 enzyme: analysis by SARs and computational docking.

J. Med. Chem. 49 , 6197-208, (2006)

Structure activity relationships for semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1) were studied using a library of arylalkylamine substrates, with the aim of contributing to the discovery of more efficient SSAO substrates. Exp...

Discovery of small molecule CXCR4 antagonists.

J. Med. Chem. 50 , 5655-5664, (2007)

In light of a proposed molecular mechanism for the C-X-C chemokine receptor type 4 (CXCR4) antagonist 1 (AMD3100), a template with the general structure 2 was designed, and 15 was identified as a lead by means of an affinity binding assay against the ligand-m...