4-Hydrazinobenzoic acid hydrochloride
4-Hydrazinobenzoic acid hydrochloride structure
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Common Name | 4-Hydrazinobenzoic acid hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 24589-77-3 | Molecular Weight | 188.612 | |
| Density | N/A | Boiling Point | 377.2ºC at 760 mmHg | |
| Molecular Formula | C7H9ClN2O2 | Melting Point | 253 °C (dec.)(lit.) | |
| MSDS | Chinese | Flash Point | 181.9ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Aortic rupture and aortic smooth muscle tumors in mice. Induction by p-hydrazinobenzoic acid hydrochloride of the cultivated mushroom Agaricus bisporus.
Lab. Invest. 57(1) , 78-85, (1987) p-Hydrazinobenzoic acid (HBA), an ingredient of the cultivated mushroom Agaricus bisporus, was given in hydrochloride form at a dosage of 0.125% in drinking water for life to randomly bred Swiss mice. Previous studies had demonstrated that either synthetic or... |
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Radical production and DNA damage induced by carcinogenic 4-hydrazinobenzoic acid, an ingredient of mushroom Agaricus bisporus.
Free Radic. Res. 40(1) , 31-9, (2006) 4-Hydrazinobenzoic acid, an ingredient of mushroom Agaricus bisporus, is carcinogenic to rodents. To clarify the mechanism of carcinogenesis, we investigated DNA damage by 4-hydrazinobenzoic acid using (32)P-labeled DNA fragments obtained from the human p53 a... |
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Development and evaluation of pH-responsive single-walled carbon nanotube-doxorubicin complexes in cancer cells.
Int. J. Nanomedicine 6 , 2889-98, (2011) Single-walled carbon nanotubes (SWNTs) have been identified as an efficient drug carrier. Here a controlled drug-delivery system based on SWNTs coated with doxorubicin (DOX) through hydrazone bonds was developed, because the hydrazone bond is more sensitive t... |
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High-throughput screening of glycan-binding proteins using miniature pig kidney N-glycan-immobilized beads.
Chem. Biol. 15(3) , 215-23, (2008) Glycan recognition leading to cell-cell interactions, signaling, and immune responses is mediated by various glycan-binding proteins (GBPs) showing highly diverse ligand specificities. We describe here a rapid glycan immobilization technique via 4-hydrazinobe... |
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Bioactivation of mushroom hydrazines to mutagenic products by mammalian and fungal enzymes.
Mutat. Res. 381(1) , 131-9, (1997) Agaritine (N2-[L-(+)-glutamyl]-4-(hydroxymethylphenyl)hydrazine), the principal hydrazine found in the edible mushroom Agaricus bisporus, as well as the N'-acetyl derivative of 4-(hydroxymethyl)phenylhydrazine and 4-(hydroxymethyl)benzene diazonium ion, as th... |
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Determination of carbohydrates as their p-sulfophenylhydrazones by capillary zone electrophoresis.
Carbohydr. Res. 332(2) , 191-6, (2001) p-Hydrazinobenzenesulfonic acid was explored as an ultraviolet labeling reagent for capillary electrophoresis of mono-, di- and trisaccharides. The labeling reaction that produces p-sulfophenylhydrazines took less than 8 min, and introduced both chromphore an... |
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Synthesis of 3-(2-aminoethyl)-5-hydroxy-1H-pyrazole derivatives. Grošelj U, et al.
ARKIVOC 3 , 49-65, (2012)
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