4-(chloromethyl)phenyl isocyanate

4-(chloromethyl)phenyl isocyanate Structure
4-(chloromethyl)phenyl isocyanate structure
Common Name 4-(chloromethyl)phenyl isocyanate
CAS Number 29173-65-7 Molecular Weight 167.59200
Density 1.216 Boiling Point 115-117ºC 10mm
Molecular Formula C8H6ClNO Melting Point 32-33ºC(lit.)
MSDS USA Flash Point >230 °F
Symbol GHS07
GHS07
Signal Word Warning

Anomeric O-acylation of Kdo using alkyl and aryl isocyanates.

Carbohydr. Res. 340(17) , 2682-7, (2005)

To develop a convenient method for the preparation of an alpha-Kdo derivative carrying a functional spacer at the reducing end, we examined anomeric O-acylation using Kdo and halogenated alkyl/aryl isocyanates as nucleophile and electrophiles, respectively. R...

Synthesis, DNA-binding activity and cytotoxicity of carbamate derivatives of Hoechst 33258 in breast cancer MCF-7 cells.

Biol. Pharm. Bull. 25(7) , 916-9, (2002)

A series of carbamate derivatives of Hoechst 33258 was prepared as potential anticancer agents. These new compounds (1-4) were readily prepared in good yields by addition of chloroethyl, bromoethyl, chloropropyl or 4-(chloromethyl)phenyl isocyanates to Hoechs...