Erythromycin Ethylsuccinate
Erythromycin Ethylsuccinate structure
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Common Name | Erythromycin Ethylsuccinate | ||
|---|---|---|---|---|
| CAS Number | 1264-62-6 | Molecular Weight | 862.053 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 874.1±65.0 °C at 760 mmHg | |
| Molecular Formula | C43H75NO16 | Melting Point | 219-224ºC | |
| MSDS | Chinese USA | Flash Point | 482.4±34.3 °C | |
| Symbol |
GHS08 |
Signal Word | Danger | |
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Hapten synthesis, monoclonal antibody production and development of a competitive indirect enzyme-linked immunosorbent assay for erythromycin in milk.
Food Chem. 171 , 98-107, (2014) Erythromycin is an antibiotic used extensively in veterinary practice worldwide for treatment, prevention and growth promotion. In this work, monoclonal antibodies (Mabs) against erythromycin were produced and used to develop a competitive indirect enzyme-lin... |
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Sensitive determination of tilmicosin, erythromycin ethylsuccinate and clindamycin by CE with electrochemiluminescence detection using azithromycin as internal standard and its applications.
J. Sep. Sci. 33(9) , 1305-11, (2010) A sensitive approach for the simultaneous determination of tilmicosin, erythromycin ethylsuccinate and clindamycin was developed by CE coupled with electrochemiluminescence detection with ionic liquid. The parameters for CE, electrochemiluminescence detection... |
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Pharmacokinetics of erythromycin after the administration of intravenous and various oral dosage forms to dogs.
J. Vet. Pharmacol. Ther. 31(6) , 496-500, (2008) The purpose of this study was to describe and compare the pharmacokinetic properties of different formulations of erythromycin in dogs. Erythromycin was administered as lactobionate (10 mg/kg, IV), estolate tablets (25 mg/kg p.o.) and ethylsuccinate tablets o... |
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Antibiotics for whooping cough (pertussis).
Cochrane Database Syst. Rev. (1) , CD004404, (2005) Whooping cough is a highly contagious disease. Infants are the population at highest risk of severe disease and death. Erythromycin for 14 days is recommended for treatment and contact prophylaxis but this regime is considered inconvenient and prolonged. The ... |
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Antibiotics for whooping cough (pertussis).
Cochrane Database Syst. Rev. (3) , CD004404, (2007) Whooping cough is a highly contagious disease. Infants are at highest risk of severe disease and death. Erythromycin for 14 days is currently recommended for treatment and contact prophylaxis, but is of uncertain benefit.To study the benefits and risks of ant... |
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Nondestructive quantitative analysis of erythromycin ethylsuccinate powder drug via short-wave near-infrared spectroscopy combined with radial basis function neural networks.
Eur. J. Pharm. Sci. 31(3-4) , 156-64, (2007) A new assay method for the nondestructive determination of erythromycin ethylsuccinate powder drug via short-wave near-infrared spectroscopy (NIR) combined with radial basis function (RBF) neural networks is investigated. The modern near-infrared spectroscopy... |
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Dose uniformity and redispersibility of pharmaceutical suspensions 2: assessment of three commercial erythromycin ethyl succinate oral liquids.
Eur. J. Pharm. Biopharm. 49(1) , 73-8, (2000) The content of active ingredient of single doses of a suspension depends to a large extent upon the redispersibility of the product. Mathematical and technical aspects of a procedure to test this property have been discussed in a preceding article. Here, the ... |
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Simultaneous determination of erythromycin ethylsuccinate and its metabolite erythromycin in human plasma using liquid chromatography-electrospray ionization mass spectrometry for clinical study.
J. Pharm. Biomed. Anal. 40(3) , 737-43, (2006) A sensitive and selective liquid chromatography-electrospray ionization mass spectrometry (LC-ESI-MS) method was developed for simultaneous identification and quantification of erythromycin ethylsuccinate and erythromycin in human plasma, which can be well ap... |
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Special feature: radiological case of the month. Denouement and discussion: acute disseminated encephalomyelitis.
Arch. Pediatr. Adolesc. Med. 154(12) , 1269-70, (2000)
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Mechanism for the degradation of erythromycin A and erythromycin A 2'-ethyl succinate in acidic aqueous solution.
J. Phys. Chem. A 111(40) , 10098-104, (2007) A major drawback of the antibiotic erythromycin A is its extreme acid sensitivity, leading to rapid inactivation in the stomach. The accepted model for degradation in aqueous acidic solution has erythromycin A in equilibrium with erythromycin A enol ether and... |