Propyl carbonochloridate

Propyl carbonochloridate Structure
Propyl carbonochloridate structure
Common Name Propyl carbonochloridate
CAS Number 109-61-5 Molecular Weight 122.550
Density 1.1±0.1 g/cm3 Boiling Point 116.2±9.0 °C at 760 mmHg
Molecular Formula C4H7ClO2 Melting Point <-70ºC
MSDS Chinese USA Flash Point 28.9±0.0 °C
Symbol GHS02 GHS05 GHS06
GHS02, GHS05, GHS06
Signal Word Danger

Vigabatrin in dried plasma spots: validation of a novel LC-MS/MS method and application to clinical practice.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 962 , 102-8, (2014)

This paper presents a LC-MS/MS method for the determination of antiepileptic drug vigabatrin in dried plasma spots (DPS). Due to its zwitterionic chemical structure, a pre-column derivatization procedure was performed, aiming to yield enhanced ionization effi...

Quantitation of pregabalin in dried blood spots and dried plasma spots by validated LC-MS/MS methods.

J. Pharm. Biomed. Anal. 109 , 79-84, (2015)

In this paper, novel LC-MS/MS methods for the determination of antiepileptic drug pregabalin in dried matrix spots (DMS) are presented. This attractive technique of sample collection in micro amount was utilized in the form of dried blood spots (DBS) and drie...

Simultaneous analysis of amphetamine-type stimulants in plasma by solid-phase microextraction and gas chromatography-mass spectrometry.

J. Anal. Toxicol. 38(7) , 432-7, (2014)

Brazil is considered one of the countries with the highest number of amphetamine-type stimulant (ATS) users worldwide, mainly diethylpropion (DIE) and fenproporex (FEN). The use of ATS is mostly linked to diverted prescription stimulants and this misuse is wi...

Liquid chromatography coupled to quadrupole-time of flight tandem mass spectrometry based quantitative structure-retention relationships of amino acid analogues derivatized via n-propyl chloroformate mediated reaction.

J. Chromatogr. A. 1403 , 70-80, (2015)

In the current study, quantitative structure-retention relationships (QSRR) were constructed based on data obtained by a LC-(ESI)-QTOF-MS/MS method for the determination of amino acid analogues, following their derivatization via chloroformate esters. Molecul...

Development of a simple and rapid solid phase microextraction-gas chromatography-triple quadrupole mass spectrometry method for the analysis of dopamine, serotonin and norepinephrine in human urine.

Anal. Chim. Acta 810 , 17-24, (2014)

The work aims at developing a simple and rapid method for the quantification of dopamine (DA), serotonin (5-HT) and norepinephrine (NE) in human urine. The urinary levels of these biogenic amines can be correlated with several pathological conditions concerni...

A reliable and simple method for the assay of neuroendocrine tumor markers in human urine by solid-phase microextraction-gas chromatography-triple quadrupole mass spectrometry.

Anal. Chim. Acta 759 , 66-73, (2013)

Homovanillic acid (HVA), vanylmandelic acid (VMA), and 5-hydroxyindoleacetic acid (5-HIAA) are the metabolites of some catecholamines such as epinephrine, nor-epinephrine, dopamine and serotonin and their quantification is used in the diagnosis and management...

Common mutation causes cystinosis in the majority of black South African patients.

Pediatr. Nephrol. 30(4) , 595-601, (2015)

The mutations responsible for cystinosis in South African patients are currently unknown. A pertinent question is whether they are similar to those described elsewhere in the world.Children who were being managed for cystinosis in the Western Cape Province of...

A Direct Aqueous Derivatization GSMS Method for Determining Benzoylecgonine Concentrations in Human Urine.

J. Forensic Sci. 60 , 1355-9, (2015)

A sensitive and reliable method for extraction and quantification of benzoylecgonine (BZE) and cocaine (COC) in urine is presented. Propyl-chloroformate was used as derivatizing agent, and it was directly added to the urine sample: the propyl derivative and C...

Dipropyl 3,6-diphenyl-1,2-dihydro-1,2,4,5-tetrazine-1,2-dicarboxylate.

Acta Crystallogr. C 59(Pt 5) , o281-2, (2003)

The title compound, C(22)H(24)N(4)O(4), was prepared from propyl chloroformate and 3,6-diphenyl-1,2-dihydro-s-tetrazine. This reaction yields the title compound rather than dipropyl 3,6-diphenyl-1,4-dihydro-s-tetrazine-1,4-dicarboxylate. The 2,3-diazabutadien...