Malononitrile
Malononitrile structure
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Common Name | Malononitrile | ||
|---|---|---|---|---|
| CAS Number | 109-77-3 | Molecular Weight | 66.061 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 218.5±0.0 °C at 760 mmHg | |
| Molecular Formula | C3H2N2 | Melting Point | 30-32 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 112.2±0.0 °C | |
| Symbol |
GHS06, GHS09 |
Signal Word | Danger | |
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Synthesis of a novel 4H-pyran analog as minor groove binder to DNA using ethidium bromide as fluorescence probe.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 152 , 165-71, (2015) In the present work, isopropyl-6-amino-4-(3,5-bis(trifluoromethyl)phenyl)-5-cyano-2-methyl-4H-pyran-3-carboxylate (4H-pyran analog) has been synthesized by a three component reaction catalyzed by CsOH/γ-Al2O3 and characterized. The interaction of 4H-pyran ana... |
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Design of donor-acceptor star-shaped oligomers for efficient solution-processible organic photovoltaics.
Faraday Discuss. 174 , 313-39, (2014) This contribution describes recent progress in the design, synthesis and properties of solution-processible star-shaped oligomers and their application in organic photovoltaics. Even though alternative chemistry has been used to design such oligomers, the mos... |
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A facile synthesis of new monoazo disperse dyes derived from 4-hydroxyphenylazopyrazole-5-amines: evaluation of microwave assisted dyeing behavior.
Molecules 17(12) , 13891-909, (2012) A series of new monoazo disperse dyes containing pyrazolopyrimidine moieties was synthesized by coupling malononitrile or 3-aminocrotononitrile with 4-hydroxy- benzenediazonium chloride. Treatment of the resulting products with hydrazine hydrate yields the co... |
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Structure-activity relationships of a novel pyranopyridine series of Gram-negative bacterial efflux pump inhibitors.
Bioorg. Med. Chem. 23(9) , 2024-34, (2015) Recently we described a novel pyranopyridine inhibitor (MBX2319) of RND-type efflux pumps of the Enterobacteriaceae. MBX2319 (3,3-dimethyl-5-cyano-8-morpholino-6-(phenethylthio)-3,4-dihydro-1H-pyrano[3,4-c]pyridine) is structurally distinct from other known G... |
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Synthesis of 2-arylamino substituted 5,6-dihydropyrido[2,3-d]pyrimidine-7(8H)-ones from arylguanidines.
Mol. Divers. 16(4) , 639-49, (2012) A practical protocol was developed for the synthesis of 2-arylamino substituted 4-amino-5,6-dihydropyrido[2,3-d]pyrimidin-7(8H)-ones from α,β-unsaturated esters, malononitrile, and an aryl substituted guanidine via the corresponding 3-aryl-3,4,5,6- tetrahydro... |
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Top-down mass spectrometry of hybrid materials with hydrophobic peptide and hydrophilic or hydrophobic polymer blocks.
Analyst 140 , 7550-64, (2015) A multidimensional mass spectrometry (MS) methodology is introduced for the molecular level characterization of polymer-peptide (or polymer-protein) copolymers that cannot be crystallized or chromatographically purified. It encompasses electrospray ionization... |
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Structural reorganization of cylindrical nanoparticles triggered by polylactide stereocomplexation.
Nat. Commun. 5 , 5746, (2014) Co-crystallization of polymers with different configurations/tacticities provides access to materials with enhanced performance. The stereocomplexation of isotactic poly(L-lactide) and poly(D-lactide) has led to improved properties compared with each homochir... |
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Device engineering for highly efficient top-illuminated organic solar cells with microcavity structures.
Adv. Mater. 24(17) , 2269-72, (2012) Small-molecule organic solar cells with microcavity structures utilizing very thin solar-absorbing active layers are simulated and fabricated. By carefully fine-tuning the in-cell spacer layer and out-of-cell capping layer, highly efficient top-illuminated in... |
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Synthesis and biological activity of 2-(bis((1,3,4-oxadiazolyl/1,3,4-thiadiazolyl)methylthio)methylene)malononitriles.
Eur. J. Med. Chem. 46 , 1367-73, (2011) The reactivity of ketene dithiolates in the presence of different equivalents of sodium ethoxide was studied. 2-(Bis((5-aryl-1,3,4-oxadiazol-2-yl)methylthio)methylene)malononitriles 5 and 2-(bis((5-aryl-1,3,4-thiadiazol-2-yl)methylthio)methylene)malononitrile... |
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An efficient three-component, one-pot synthesis of 2-alkylthio-4-amino-5-cyano-6-aryl(alkyl)pyrimidines in water.
Mol. Divers. 16(3) , 431-9, (2012) A convenient and practical method for the synthesis of 2-alkylthio-4-amino-5-cyano-6-aryl(alkyl)pyrimidines has been developed via a three-component, one-pot reaction from aldehydes, malononitrile and S-alkylisothiouronium salts in water at room temperature. ... |