BR1

BR1 Structure
BR1 structure
Common Name BR1
CAS Number 893449-38-2 Molecular Weight 485.21300
Density N/A Boiling Point N/A
Molecular Formula C17H11Br2NO2S2 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

Synthesis and biological evaluation of rhodanine derivatives as PRL-3 inhibitors.

Bioorg. Med. Chem. Lett. 16 , 2996-2999, (2006)

A series of rhodanine derivatives was synthesized and evaluated for their ability to inhibit PRL-3. Benzylidene rhodanine derivative showed good biological activity, while compound 5e was the most active in this series exhibiting an IC50 value of 0.9 microM i...