2-Amino-5-chlorophenol
2-Amino-5-chlorophenol structure
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Common Name | 2-Amino-5-chlorophenol | ||
|---|---|---|---|---|
| CAS Number | 28443-50-7 | Molecular Weight | 143.571 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 267.7±25.0 °C at 760 mmHg | |
| Molecular Formula | C6H6ClNO | Melting Point | 145-153 °C(lit.) | |
| MSDS | USA | Flash Point | 115.7±23.2 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Chemoselective nitro group reduction and reductive dechlorination initiate degradation of 2-chloro-5-nitrophenol by Ralstonia eutropha JMP134.
Appl. Environ. Microbiol. 65(6) , 2317-23, (1999) Ralstonia eutropha JMP134 utilizes 2-chloro-5-nitrophenol as a sole source of nitrogen, carbon, and energy. The initial steps for degradation of 2-chloro-5-nitrophenol are analogous to those of 3-nitrophenol degradation in R. eutropha JMP134. 2-Chloro-5-nitro... |
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Nephrotoxic potential of 2-amino-5-chlorophenol and 4-amino-3-chlorophenol in Fischer 344 rats: comparisons with 2- and 4-chloroaniline and 2- and 4-aminophenol.
Toxicology 108(1-2) , 109-23, (1996) Nephrotoxicity occurs following intraperitoneal (i.p.) administration of 2-chloroaniline or 4-chloroaniline hydrochloride to Fischer 344 rats, but the nephrotoxicant chemical species and mechanism of nephrotoxicity are unknown. The purpose of this study was t... |
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Novel partial reductive pathway for 4-chloronitrobenzene and nitrobenzene degradation in Comamonas sp. strain CNB-1.
Appl. Environ. Microbiol. 72(3) , 1759-65, (2006) Comamonas sp. strain CNB-1 grows on 4-chloronitrobenzene (4-CNB) and nitrobenzene as sole carbon and nitrogen sources. In this study, two genetic segments, cnbB-orf2-cnbA and cnbR-orf1-cnbCaCbDEFGHI, located on a newly isolated plasmid, pCNB1 (ca. 89 kb), and... |
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Initial reactions in the biodegradation of 1-chloro-4-nitrobenzene by a newly isolated bacterium, strain LW1.
Appl. Environ. Microbiol. 65(4) , 1405-12, (1999) Bacterial strain LW1, which belongs to the family Comamonadaceae, utilizes 1-chloro-4-nitrobenzene (1C4NB) as a sole source of carbon, nitrogen, and energy. Suspensions of 1C4NB-grown cells removed 1C4NB from culture fluids, and there was a concomitant releas... |
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Characterization of genes involved in the initial reactions of 4-chloronitrobenzene degradation in Pseudomonas putida ZWL73.
Appl. Microbiol. Biotechnol. 73(1) , 166-71, (2006) The genes encoding enzymes involved in the initial reactions during degradation of 4-chloronitrobenzene (4CNB) were characterized from the 4CNB utilizer Pseudomonas putida ZWL73, in which a partial reductive pathway was adopted. A DNA fragment containing gene... |
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2-Amino-5-chlorophenol toxicity in renal cortical slices from Fischer 344 rats: effect of antioxidants and sulfhydryl agents.
Toxicol. Appl. Pharmacol. 161(1) , 1-9, (1999) 2-Amino-5-chlorophenol is nephrotoxic through an unidentified mechanism. This study examined the in vitro toxicity of 2-amino-5-chlorophenol in renal cortical slices from Fischer 344 rats and specifically assessed induction of lipid peroxidation and depletion... |
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A novel 2-aminophenol 1,6-dioxygenase involved in the degradation of p-chloronitrobenzene by Comamonas strain CNB-1: purification, properties, genetic cloning and expression in Escherichia coli.
Arch. Microbiol. 183(1) , 1-8, (2005) Comamonas strain CNB-1 was isolated from a biological reactor treating wastewater from a p-chloronitrobenzene production factory. Strain CNB-1 used p-chloronitrobenzene as sole source of carbon, nitrogen, and energy. A 2-aminophenol 1,6-dioxygenase was purifi... |
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Synthesis, characterization, and antimicrobial activity of cobalt (II), nickel (II), copper (II) and zinc (II) complexes with ferrocenyl Schiff bases containing a phenol moiety. Abd-Elzaher MM.
Appl. Organomet. Chem. 18(4) , 149-155, (2004)
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Synthesis and Crystal Structure of 1-Chloro-2-methyl-4-nitrobenzene. Saeed A and Simpson J.
Crystals 2(1) , 137-143, (2012)
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Anacardic acid derived salicylates are inhibitors or activators of lipoxygenases. Wisastra R, et al.
Bioorg. Med. Chem. 20(12) , 5027-5032, (2012)
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