1,10-Phenanthroline-5,6-dione
1,10-Phenanthroline-5,6-dione structure
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Common Name | 1,10-Phenanthroline-5,6-dione | ||
|---|---|---|---|---|
| CAS Number | 27318-90-7 | Molecular Weight | 210.188 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 456.1±20.0 °C at 760 mmHg | |
| Molecular Formula | C12H6N2O2 | Melting Point | 260ºC (dec.) | |
| MSDS | USA | Flash Point | 229.1±28.2 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Photoinduced intercalation and coordination of a dirhodium complex to DNA: dual DNA binding.
ChemMedChem 9(6) , 1260-5, (2014) Two new complexes, cis-H,H-[Rh2 (OCCH3 NH)2 (LL)(CH3 CN)2 ](2+) , where LL=bpy (2, bpy=2,2'-bipyridine) and dppz (3, dppz=dipyrido[3,2-a:2',3'-c]phenazine), were prepared from the reaction of cis-H,H-[Rh2 (OCCH3 NH)2 (CH3 CN)6 ](2+) (1) with the corresponding... |
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Luminescent pH sensor of a novel imidazole-containing hexanuclear Ru(II) polypyridyl complex.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 114 , 159-63, (2013) Hexapodal ligand H6L containing imidazole rings has been prepared by the reaction of 1,10-phenanthroline-5,6-dione with 1,2,3,4,5,6-hexakis[(3-formylphenoxy)methyl]benzene. The Ru(II) polypyridyl complex [{Ru(bpy)2}6(μ6-H6L)](PF6)12 (bpy=2,2'-bipyridine) has ... |
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Synthesis and physicochemical properties of novel lophine derivatives as chemiluminescent in vitro activators for detection of free radicals.
Eur. Biophys. J. 44 , 623-34, (2015) The overproduction of free radicals and reactive oxygen species (ROS) has been proved as a basic damage mechanism and cause for oxidative stress. Their measurement is often hindered by the low signal. This could be resolved with the application of luminescent... |
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Electrochemical biosensor based on glucose oxidase encapsulated within enzymatically synthesized poly(1,10-phenanthroline-5,6-dione).
Colloids Surf. B Biointerfaces 123 , 685-91, (2014) This study is focused on the investigation of electrocatalytic effect of glucose oxidase (GOx) immobilized on the graphite rod (GR) electrode. The enzyme modified electrode was prepared by encapsulation of immobilized GOx within enzymatically formed poly(1,10... |
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In vitro anti-tumour effect of 1,10-phenanthroline-5,6-dione (phendione), [Cu(phendione)3](ClO4)2.4H2O and [Ag(phendione)2]ClO4 using human epithelial cell lines.
Chem. Biol. Interact. 164(1-2) , 115-25, (2006) The anti-cancer chemotherapeutic potential of 1,10-phenanthroline-5,6-dione (phendione), [Cu(phendione)(3)](ClO(4))(2).4H(2)O and [Ag(phendione)(2)]ClO(4) were determined using four human cells lines, i.e. two neoplastic (A-498 and Hep-G2) and two non-neoplas... |
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Mixed-ligand copper(II) maltolate complexes: synthesis, characterization, DNA binding and cleavage, and cytotoxicity.
Inorg. Chem. 48(19) , 9120-32, (2009) The mixed-ligand complexes [Cu(L)(maltol)] where L = 2,2'-bipyridine (bpy; 1), 1,10-phenanthroline (phen; 2), 1,10-phenanthroline-5,6-dione (phendione; 3), dipyrido[3,2-a:2',3'-c]phenazine (dppz; 4), and 4b,5,7,7a-tetrahydro-4b,7a-epiminomethanoimino-6H-imida... |
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Effects of 1,7- and 1,10-phenanthroline dione on tissue culture cells.
Biochem. Pharmacol. 32(1) , 172-4, (1983)
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Photophysical studies of fused phenanthrimidazole derivatives as versatile π-conjugated systems for potential NLO applications.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 92 , 113-21, (2012) Two new heterocyclic imidazole derivatives consists of π-conjugated system attached to a phenanthrimidazole moiety have been synthesized in moderate yield by the condensation of 1,10-phenanthroline-5,6-dione with substituted aromatic aldehydes and 4-methoxyan... |
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Synthesis and X-ray crystal structure of [Ag(phendio)2]ClO4 (phendio = 1,10-phenanthroline-5,6-dione) and its effects on fungal and mammalian cells.
Biometals 17(6) , 635-45, (2004) The Cu(II) and Ag(I) complexes, [Cu(phendio)3](ClO4)2 x 4H2O and [Ag(phendio)2]ClO4 (phendio = 1,10-phenanthroline-5,6-dione), are prepared in good yield by reacting phendio with the appropriate metal perchlorate salt. The X-ray crystal structure of the Ag(I)... |
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Metal complexes of 1,10-phenanthroline-5,6-dione alter the susceptibility of the yeast Candida albicans to amphotericin B and miconazole.
Biometals 17(4) , 415-22, (2004) Growth of the pathogenic yeast Candida albicans in sub-MIC (minimum inhibitory concentration) levels of Cu(ClO4)2 6H2O and [Cu(phendio)3](ClO4)2 4H2O (phendio = 1,10-phenanthroline-5,6-dione) increased the concentration of miconazole and amphotericin B requir... |