Thiosemicarbazide
Thiosemicarbazide structure
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Common Name | Thiosemicarbazide | ||
|---|---|---|---|---|
| CAS Number | 79-19-6 | Molecular Weight | 91.14 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 208.6±23.0 °C at 760 mmHg | |
| Molecular Formula | CH5N3S | Melting Point | 180-183 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 80.0±22.6 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Carbamylation of immunoglobulin abrogates activation of the classical complement pathway.
Eur. J. Immunol. 44(11) , 3403-12, (2014) Post-translational modifications of proteins significantly affect their structure and function. The carbamylation of positively charged lysine residues to form neutral homoitrulline occurs primarily under inflammatory conditions through myeloperoxidase-depend... |
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Rhenium mixed-ligand complexes with S,N,S-tridentate thiosemicarbazone/thiosemicarbazide ligands.
Dalton Trans. 42(14) , 5111-21, (2013) Rhenium(V) complexes containing tridentate thiosemicarbazones/thiosemicarbazides (H2L1) derived from N-[N′,N′-dialkylamino(thiocarbonyl)]benzimidoyl chlorides with 4,4-dialkylthiosemicarbazides have been synthesized by ligand-exchange reactions starting from ... |
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Synthesis and antityrosinase mechanism of benzaldehyde thiosemicarbazones: novel tyrosinase inhibitors.
J. Agric. Food Chem. 60(6) , 1542-7, (2012) p-Hydroxybenzaldehyde thiosemicarbazone (HBT) and p-methoxybenzaldehyde thiosemicarbazone (MBT) were synthesized and established by (1)H NMR and mass spectra. Both compounds were evaluated for their inhibition activities on mushroom tyrosinase and free-cell t... |
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A metal-organic tetrahedron as a redox vehicle to encapsulate organic dyes for photocatalytic proton reduction.
J. Am. Chem. Soc. 137(11) , 3967-74, (2015) The design of artificial systems that mimic highly evolved and finely tuned natural photosynthetic systems is a subject of intensive research. We report herein a new approach to constructing supramolecular systems for the photocatalytic generation of hydrogen... |
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Single-fluorophore-based fluorescent probes enable dual-channel detection of Ag⁺ and Hg²⁺ with high selectivity and sensitivity.
Anal. Chim. Acta 839 , 74-82, (2014) A new type of fluorescent probe capable of detecting Ag(+) and Hg(2+) in two independent channels was developed in the present work. Specifically, in CH3CN-MOPS mixed solvents with CH3CN/MOPS ratio (v/v) of 15/85, this type of probe fluoresced weakly, and the... |
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Preparation, characterization and application of thiosemicarbazide grafted multiwalled carbon nanotubes for solid-phase extraction of Cd(II), Cu(II) and Pb(II) in environmental samples.
J. Environ. Sci. (China) 25(11) , 2331-7, (2013) Thiosemicarbazide-grafted multi-walled carbon nanotubes were prepared and employed to investigate the pre-concentration of Cd(II), Cu(II) and Pb(II) from aqueous solution prior to their determination by ICP-OES. The resulting material was characterized by FT-... |
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Rhodamine-modified upconversion nanophosphors for ratiometric detection of hypochlorous acid in aqueous solution and living cells.
Small 10(17) , 3560-7, (2014) Hypochlorous acid (HOCl), a reactive oxygen species (ROS) produced by myeloperoxidase (MPO) enzyme-mediated peroxidation of chloride ions, acts as a key microbicidal agent in immune systems. However, misregulated production of HOCl could damage host tissues a... |
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3-mercapto-1,2,4-triazoles and N-acylated thiosemicarbazides as metallo-β-lactamase inhibitors.
Bioorg. Med. Chem. Lett. 22 , 380-6, (2012) The production of β-lactamases is an effective strategy by which pathogenic bacteria can develop resistance against β-lactam antibiotics. While inhibitors of serine-β-lactamases are widely used in combination therapy with β-lactam antibiotics, there are no cl... |
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Neutral gold complexes with tridentate SNS thiosemicarbazide ligands.
Inorg. Chem. 51(3) , 1604-13, (2012) Na[AuCl(4)]·2H(2)O reacts with tridentate thiosemicarbazide ligands, H(2)L1, derived from N-[N',N'-dialkylamino(thiocarbonyl)]benzimidoyl chloride and thiosemicarbazides under formation of air-stable, green [AuCl(L1)] complexes. The organic ligands coordinate... |
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Novel bis-C,N-cyclometalated iridium(III) thiosemicarbazide antitumor complexes: interactions with human serum albumin and DNA, and inhibition of cathepsin B.
Inorg. Chem. 52(2) , 974-82, (2013) A series of new organoiridium(III) complexes [Ir(N-C)(2)(N-S)]Cl (HN-C = 2-phenylpyridine (Hppy), N-S = methyl thiosemicarbazide (1), phenyl thiosemicarbazide (2) and naphtyl thiosemicarbazide (3)) have been synthesized and characterized. The crystal structur... |