trans-Cyclohexane-1,4-diamine
trans-Cyclohexane-1,4-diamine structure
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Common Name | trans-Cyclohexane-1,4-diamine | ||
|---|---|---|---|---|
| CAS Number | 2615-25-0 | Molecular Weight | 114.189 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 199.4±8.0 °C at 760 mmHg | |
| Molecular Formula | C6H14N2 | Melting Point | 67-72 °C | |
| MSDS | Chinese USA | Flash Point | 80.0±0.0 °C | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
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Trans-cyclohexanediamines prevent thermal inactivation of protein: role of hydrophobic and electrostatic interactions.
Protein J. 27(4) , 253-7, (2008) Although solution additives prevent protein misfolding, the mechanism remains elusive. In this paper, we compare the preventive effects of trans-1,2-cyclohexanediamine (1,2-CHDA) and trans-1,4-cyclohexanediamine (1,4-CHDA) on the heat-induced inactivation of ... |
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Preparation and characterization of nanoporous thin films from fully aliphatic polyimides.
J. Nanosci. Nanotechnol. 11(7) , 6141-7, (2011) Fully aliphatic polyimides (APIs) were prepared from rel-(1'R,3S5'S)-spiro[furan-3(2H),6'-[3]oxabicyclo[3.2.1]octane]-2,2',4',5(4H)-tetrone (DAn) as unsymmetrical spiro dianhydride, and either cis-trans-1,4-diaminocyclohexane (mix-DACH) or trans-1,4-diaminocy... |
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Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring Pt II chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand.
Biochem. Pharmacol. 79(4) , 552-64, (2010) Earlier studies have described promising antitumor activity of a large-ring chelate complex [PtCl(2)(cis-1,4-DACH)] (DACH=diaminocyclohexane). Encouraging antitumor activity of this analogue of cisplatin prompted us to perform studies focused on the mechanist... |
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Synthesis, structural characterization, and antitumor properties of a novel class of large-ring platinum(II) chelate complexes incorporating the cis-1,4-diaminocyclohexane ligand in a unique locked boat conformation.
J. Med. Chem. 37(17) , 2630-6, (1994) The first two analogs 5a,b of a new class of neutral large-ring square-planar Pt(II) chelate complexes of the generic structure [Pt(cis-1,4-dach)X2] were synthesized via a refined technique, structurally characterized by NMR (1H, 13C, 195Pt), FAB mass spectro... |
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cis-1,4-diaminocyclohexane-Pt(II) and -(IV) adducts with DNA bases and nucleosides.
J. Inorg. Biochem. 96(4) , 452-6, (2003) A series of new platinum(II) and platinum(IV) adducts of type [P(II)(cis-1,4-DACH)LCl]NO(3,) where cis-1,4-DACH=cis-1,4-diaminocyclohexane, and L=9-ethylguanine, 1-methylcytosine, adenine, adenosine, cytosine, cytidine, guanine, and [Pt(IV)(cis-1,4-DACH)Ltran... |
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Convergent and stereospecific synthesis of molecules containing alpha-functionalized guanidiniums via alpha-guanidino acids.
J. Org. Chem. 72(25) , 9834-7, (2007) To introduce chirality and functional groups adjacent to guanidiniums to modulate specificity and affinity in recognition, N,N'-bis(Boc)-alpha-guanidino acids were synthesized from alpha-amino acid methyl esters. Protected alpha-guanidino acids coupled to cyc... |
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Purification and characterization of amine oxidase from pea seedlings.
Protein Expr. Purif. 15(2) , 196-201, (1999) A novel, simple, and rapid procedure for the purification of pea seedling amine oxidase is reported. The crude enzyme, obtained by ammonium sulfate fractionation, was purified in two steps: the first one by anion-exchange chromatography and the second one by ... |
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Synthesis and structure of a new layered zinc phosphate [C 6 N 2 H 1 6] 3. 5 [Zn 1 4 (PO 4) 7 (HPO 4) 7] in the presence of trans-1, 4-diaminocyclohexane. Xing Y, et al.
Inorg. Chem. Commun. 7(4) , 475-77, (2004)
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