2-Chloropyrazine

2-Chloropyrazine Structure
2-Chloropyrazine structure
Common Name 2-Chloropyrazine
CAS Number 14508-49-7 Molecular Weight 114.533
Density 1.3±0.1 g/cm3 Boiling Point 155.3±20.0 °C at 760 mmHg
Molecular Formula C4H3ClN2 Melting Point N/A
MSDS Chinese USA Flash Point 57.8±0.0 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning

Cobalt-catalyzed cross-coupling between in situ prepared arylzinc halides and 2-chloropyrimidine or 2-chloropyrazine.

J. Org. Chem. 74(8) , 3221-4, (2009)

A cobalt-catalyzed cross-coupling of aryl halides with 2-chloropyrimidines or 2-chloropyrazines is reported in satisfactory to high yields. The key step of this procedure is the formation of aromatic organozinc reagents and their coupling with 2-chlorodiazine...

Gas chromatographic assay for the new antitumor agent pyrazine-2-diazohydroxide (diazohydroxide) and its stability in buffer, blood and plasma.

J. Chromatogr. A. 383(1) , 77-83, (1986)

Diazohydroxide is a new antitumor agent being considered for clinical trial. A sensitive and specific assay for diazohydroxide in physiological media, plasma and blood has been developed based on conversion of diazohydroxide to 2-chloropyrazine in the presenc...