Adenosine 3'-Phosphate 5'-Phosphosulfate Lithium salt

Adenosine 3'-Phosphate 5'-Phosphosulfate Lithium salt Structure
Adenosine 3'-Phosphate 5'-Phosphosulfate Lithium salt structure
Common Name Adenosine 3'-Phosphate 5'-Phosphosulfate Lithium salt
CAS Number 109434-21-1 Molecular Weight 514.20500
Density N/A Boiling Point N/A
Molecular Formula C10H15LiN5O13P2S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Expression and the role of 3'-phosphoadenosine 5'-phosphosulfate transporters in human colorectal carcinoma.

Glycobiology 21 , 235-246, (2011)

Sulfation represents an essential modification for various molecules and regulates many biological processes. The sulfation of glycans requires a specific transporter for 3'-phosphoadenosine 5'-phosphosulfate (PAPS) on the Golgi apparatus. This study investig...

Stimulation of purinergic receptors modulates chemokine expression in human keratinocytes.

J. Invest. Dermatol. 127 , 660-7, (2007)

ATP is abundantly released from stressed or damaged cells in response to mechanical stimulation, bacteria, or noxious agents. In this study, we have investigated the possible involvement of P2 receptors (receptor for extracellular nucleotides) in the expressi...

Expression of heparan sulfate sulfotransferases in Kluyveromyces lactis and preparation of 3'-phosphoadenosine-5'-phosphosulfate.

Glycobiology 21 , 771-780, (2011)

Heparan sulfate (HS) belongs to a major class of glycans that perform central physiological functions. Heparin is a specialized form of HS and is a clinically used anticoagulant drug. Heparin is a natural product isolated from pig intestine. There is a strong...

Target selection of heparan sulfate hexuronic acid 2-O-sulfotransferase.

Glycobiology 20 , 1274-1282, (2010)

The signaling of various molecules involved in development and regulation of cell growth are regulated by heparan sulfate (HS). Specific binding of HS to ligand proteins depends on the HS sulfation pattern, where the spacing and number of O-sulfate groups are...

Sulfate in fetal development.

Semin. Cell. Dev. Biol. 22(6) , 653-659, (2011)

Sulfate (SO(4)(2-)) is an important nutrient for human growth and development, and is obtained from the diet and the intra-cellular metabolism of sulfur-containing amino acids, including methionine and cysteine. During pregnancy, fetal tissues have a limited ...

Cloning and characterization of a mammalian lithium-sensitive bisphosphate 3'-nucleotidase inhibited by inositol 1,4-bisphosphate.

J. Biol. Chem. 274 , 13619-28, (1999)

Discovery of a structurally conserved metal-dependent lithium-inhibited phosphomonoesterase protein family has identified several potential cellular targets of lithium as used to treat manic depression. Here we describe identification of a novel family member...

Studies on bovine adrenal estrogen sulfotransferase. III. Facile synthesis of 3'-phospho- and 2'-phosphoadenosine 5'-phosphosulfate.

Biochim. Biophys. Acta 480 , 376, (1977)

A practical synthesis of 3'-phosphoadenosine 5'-phosphosulfate (IV) in yields of 68-72% from adenosine 2',3'-cyclic phosphate 5'-phosphate (II) is described. Reaction of II with triethylamine-N-sulfonic acid affords adenosine 2',3'-cyclic phosphate 5'-phospho...

Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays.

Anal. Biochem. 423 , 86-92, (2012)

Sulfotransferases are a large group of enzymes that transfer a sulfonate group from the donor substrate, 3'-phosphoadenosine-5'-phosphosulfate (PAPS)(1), to various acceptor substrates, generating 3'-phosphoadenosine-5'-phosphate (PAP) as a by-product. A univ...

Cooper, B.P. and Baumgarten, F.E.

Z. Naturforsch. 159 , (1980)