terbinafine hydrochloride

terbinafine hydrochloride Structure
terbinafine hydrochloride structure
Common Name terbinafine hydrochloride
CAS Number 78628-80-5 Molecular Weight 327.891
Density 1.007g/cm3 Boiling Point 417.9ºC at 760 mmHg
Molecular Formula C21H26ClN Melting Point 204-208°C
MSDS Chinese USA Flash Point 183.7ºC
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

A rapid method for determination of 22 selected drugs in human urine by UHPLC/MS/MS for clinical application.

J. AOAC Int. 97(6) , 1526-37, (2015)

A rapid and sensitive ultra-HPLC/MSIMS (UHPLC/MSIMS) assay method for the simultaneous determination in human urine of 22 drugs belonging to different pharmaceutical groups was developed. The drugs were extracted from urine samples and then separated on a Zor...

Production of squalene by lactose-fermenting yeast Kluyveromyces lactis with reduced squalene epoxidase activity.

Lett. Appl. Microbiol. 61 , 77-84, (2015)

Utilization of yeast as squalene source for commercial use is limited by relatively high production costs. The ability of Kluyveromyces lactis to grow on cheap lactose-containing diary industry wastes could improve the economy of the production process. We th...

Selective extraction of antimycotic drugs from sludge samples using matrix solid-phase dispersion followed by on-line clean-up.

Anal. Bioanal. Chem 407(3) , 907-17, (2015)

An effective and selective, modular sample preparation method for the extraction of eight antimycotic drugs, belonging to three different chemical classes, from digested sludge samples is proposed. To this end, matrix solid-phase dispersion (MSPD) was on-line...

Global analysis of fungal morphology exposes mechanisms of host cell escape.

Nat. Commun. 6 , 6741, (2015)

Developmental transitions between single-cell yeast and multicellular filaments underpin virulence of diverse fungal pathogens. For the leading human fungal pathogen Candida albicans, filamentation is thought to be required for immune cell escape via inductio...

DrugBank 3.0: a comprehensive resource for 'omics' research on drugs.

Nucleic Acids Res. 39 , D1035-41., (2011)

DrugBank (http://www.drugbank.ca) is a richly annotated database of drug and drug target information. It contains extensive data on the nomenclature, ontology, chemistry, structure, function, action, pharmacology, pharmacokinetics, metabolism and pharmaceutic...

Stability of terbinafine hydrochloride in an extemporaneously prepared oral suspension at 25 and 4 degrees C.

Am. J. Health Syst. Pharm. 56 , 243-245, (1999)

The stability of terbinafine 25 mg/mL (as the hydrochloride salt) in an extemporaneously prepared oral suspension at 25 and 4 degrees C was studied. Twenty 250-mg terbinafine tablets were crushed to a fine powder and diluted to a concentration of 25 mg/mL wit...

Adsorption, partition and release balances of terbinafine hydrochloride, part I.

Pharmazie 62 , 273-277, (2007)

In this study the adsorption, partition and releasing balances of terbinafine hydrochloride have been studied. The adsorption isotherms of antifugal drug terbinafine hydrochloride (terbinafine), on the base of its adsorption from aqueous solutions on the surf...

Successful treatment of Batrachochytrium salamandrivorans infections in salamanders requires synergy between voriconazole, polymyxin E and temperature.

Sci. Rep. 5 , 11788, (2015)

Chytridiomycosis caused by the chytrid fungus Batrachochytrium salamandrivorans (Bsal) poses a serious threat to urodelan diversity worldwide. Antimycotic treatment of this disease using protocols developed for the related fungus Batrachochytrium dendrobatidi...