Ciliobrevin A
Ciliobrevin A structure
|
Common Name | Ciliobrevin A | ||
|---|---|---|---|---|
| CAS Number | 302803-72-1 | Molecular Weight | 358.17800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H9Cl2N3O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
|
Effects of the dynein inhibitor ciliobrevin on the flagellar motility of sea urchin spermatozoa.
Cytoskeleton (Hoboken.) 72 , 182-92, (2015) Ciliobrevin has recently been found to be a membrane-permeable inhibitor that is specific to AAA+ molecular motors such as cytoplasmic dyneins. In this study, we investigated how ciliobrevin inhibited the motility of sperm from sea urchins: Hemicentrotus pulc... |
|
|
The fate of the primary cilium during myofibroblast transition.
Mol. Biol. Cell 25(5) , 643-57, (2014) Myofibroblasts, the culprit of organ fibrosis, can originate from mesenchymal and epithelial precursors through fibroblast-myofibroblast and epithelial-myofibroblast transition (EMyT). Because certain ciliopathies are associated with fibrogenesis, we sought t... |
|
|
Polarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse.
Mol. Biol. Cell 26(7) , 1273-85, (2015) B-cell receptor (BCR) engagement with surface-tethered antigens leads to the formation of an immune synapse, which facilitates antigen uptake for presentation to T-lymphocytes. Antigen internalization and processing rely on the early dynein-dependent transpor... |
|
|
Distinct modes of mitotic spindle orientation align cells in the dorsal midline of ascidian embryos.
Dev. Biol. 408 , 66-78, (2015) The orientation of cell division can have important consequences on the choice of cell fates adopted by each daughter cell as well as on the architecture of the tissue within which the dividing cell resides. We have studied in detail the oriented cell divisio... |
|
|
Hedgehog pathway inhibitor-4 suppresses malignant properties of chondrosarcoma cells by disturbing tumor ciliogenesis.
Oncol. Rep. 32(4) , 1622-30, (2014) Chondrosarcoma is a type of malignant bone tumor secreting cartilage-like matrix. In clinical treatment, there is no frequently used drug treatment option except for surgical resection. Hedgehog (HH) pathway is a classical signaling pathway that regulates nor... |