Paroxetine HCl
Paroxetine HCl structure
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Common Name | Paroxetine HCl | ||
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| CAS Number | 78246-49-8 | Molecular Weight | 365.826 | |
| Density | 1.213 g/cm3 | Boiling Point | 451.7ºC at 760 mmHg | |
| Molecular Formula | C19H21ClFNO3 | Melting Point | 129-131ºC | |
| MSDS | N/A | Flash Point | 227ºC | |
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Paroxetine (Brisdelle) for hot flashes.
Med. Lett. Drugs Ther. 55(1428) , 85-6, (2013)
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FDA Approval of Paroxetine for Menopausal Hot Flushes
N. Engl. J. Med. 370(19) , 1777-9, (2014) An FDA advisory committee recommended against approving paroxetine for menopausal vasomotor symptoms. But recognizing the lack of hormone-free products for this indication, and after reviewing the drug's efficacy and safety, the FDA decided it can benefit som... |
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Serotonin and yawning: a potential adverse drug reaction during antidepressant therapy
Presse Med. 43(10 Pt 1) , 1135-6, (2014)
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Paroxetine approval.
Am. J. Nurs. 114(1) , 10, (2014)
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Putting GlaxoSmithKline to the test over paroxetine.
BMJ 347 , f6754, (2013)
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Incremental cost-effectiveness of pharmacotherapy and two brief cognitive-behavioral therapies compared with usual care for panic disorder and noncardiac chest pain.
J. Nerv. Ment. Dis. 201(9) , 753-9, (2013) The aim of this study was to assess the incremental cost-effectiveness ratios (ICERs) of two brief cognitive-behavioral therapy (CBT)-based interventions and a pharmacological treatment, compared with usual care, initiated in the emergency department (ED) for... |
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Physicians' prescribing preferences were a potential instrument for patients' actual prescriptions of antidepressants.
J. Clin. Epidemiol. 66(12) , 1386-96, (2013) To investigate whether physicians' prescribing preferences were valid instrumental variables for the antidepressant prescriptions they issued to their patients.We investigated whether physicians' previous prescriptions of (1) tricyclic antidepressants (TCAs) ... |
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SSRI versus bupropion effects on symptom clusters in suicidal depression: post hoc analysis of a randomized clinical trial.
J. Clin. Psychiatry 74(9) , 872-9, (2013) Identifying the depression symptoms most closely associated with suicidal thoughts and which medications provide the fastest depression relief may help suicide prevention.Post hoc analysis of data from a randomized, double-blind, 8-week clinical trial of the ... |
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Anti-depressant like activity of N-n-butyl-3-methoxyquinoxaline-2-carboxamide (6o) a 5-HT3 receptor antagonist.
Indian J. Exp. Biol. 51(6) , 435-43, (2013) The compound 6o (at 0.5, 1 and 2 mg/kg, ip) with optimum log P and pA2 value, was subjected to forced swim test (FST) and tail suspension test (TST). The compound 6o significantly reduced the duration of immobility in mice without affecting the base line loco... |
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Different serum BDNF levels in depression: results from BDNF studies in FYR Macedonia and Bulgaria.
Psychiatr. Danub. 25(2) , 123-7, (2013) A growing body of evidence shows that brain-derived neurotrophic factor (BDNF) plays a role in depressive disorder. Serum BDNF levels are lower in depressed patients and they increase after a long course of antidepressant treatment. Our study aims to test the... |