Minoxidil
Minoxidil structure
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Common Name | Minoxidil | ||
|---|---|---|---|---|
| CAS Number | 38304-91-5 | Molecular Weight | 209.248 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 351.7±45.0 °C at 760 mmHg | |
| Molecular Formula | C9H15N5O | Melting Point | 272-274 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 166.5±28.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Phase II metabolism in human skin: skin explants show full coverage for glucuronidation, sulfation, N-acetylation, catechol methylation, and glutathione conjugation.
Drug Metab. Dispos. 43(1) , 126-39, (2014) Although skin is the largest organ of the human body, cutaneous drug metabolism is often overlooked, and existing experimental models are insufficiently validated. This proof-of-concept study investigated phase II biotransformation of 11 test substrates in fr... |
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Intestinal permeability study of minoxidil: assessment of minoxidil as a high permeability reference drug for biopharmaceutics classification.
Mol. Pharm. 12(1) , 204-11, (2015) The purpose of this study was to evaluate minoxidil as a high permeability reference drug for Biopharmaceutics Classification System (BCS). The permeability of minoxidil was determined in in situ intestinal perfusion studies in rodents and permeability studie... |
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Fabrication of an electrochemical sensor based on computationally designed molecularly imprinted polymer for the determination of mesalamine in real samples.
Mater. Sci. Eng. C. Mater. Biol. Appl. 55 , 209-17, (2015) A novel electrochemical sensor based on mesalamine molecularly imprinted polymer (MIP) film on a glassy carbon electrode was fabricated. Density functional theory (DFT) in gas and solution phases was developed to study the intermolecular interactions in the p... |
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Potassium channel openers increase aortic elastic fiber formation and reverse the genetically determined elastin deficit in the BN rat.
Hypertension 62(4) , 794-801, (2013) Hypertension is a cardiovascular disorder that appears in more than half of the patients with Williams-Beuren syndrome, hemizygous for the elastin gene among 26 to 28 other genes. It was shown that the antihypertensive drug minoxidil, an ATP-dependent potassi... |
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Diffuse pattern essential syphilitic alopecia: an unusual form of secondary syphilis.
Int. J. Dermatol. 51(8) , 1006-7, (2012)
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Topical minoxidil for hair loss in women.
DICP 24(11) , 1062-3, (1990)
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Alopecia Areata: a possible extraintestinal manifestation of Crohn's disease.
J. Crohns. Colitis 6(9) , 962-3, (2012)
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Pseudofolliculitis barbae induced by oral minoxidil.
Clin. Exp. Dermatol. 37(7) , 800-1, (2012)
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Efficacy and safety of bimatoprost 0.03% versus minoxidil 3% in enhancement of eyebrows: a randomized, double-blind, split-face comparative study.
J. Dermatol. 39(10) , 865-6, (2012)
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What's new in androgenetic alopecia: approvals, long-term safety data, cancer risk and treatment options for women.
Journal. of. Drugs in. Dermatology. 10(1) , 98-101, (2011)
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