3,5-diisopropylsalicylic acid

3,5-diisopropylsalicylic acid Structure
3,5-diisopropylsalicylic acid structure
Common Name 3,5-diisopropylsalicylic acid
CAS Number 2215-21-6 Molecular Weight 222.28000
Density 1.108g/cm3 Boiling Point 324.5ºC at 760mmHg
Molecular Formula C13H18O3 Melting Point 113-115 °C(lit.)
MSDS Chinese USA Flash Point 164.3ºC
Symbol GHS07
GHS07
Signal Word Warning

Copper(II) interaction with 3,5-diisopropylsalicylic acid (Dips): new insights on its role as a potential *OH inactivating ligand.

J. Inorg. Biochem. 101(4) , 565-77, (2007)

The purpose of this study was to identify the low molecular mass complexes formed between copper(II) and 3,5-diisopropylsalicylic acid (Dips) in physiological conditions. Copper(II)-Dips complex equilibria were determined using glass electrode potentiometry a...

Effects of some non-steroidal anti-inflammatory drug copper complexes on polymorphonuclear leukocyte oxidative metabolism.

Agents Actions 31(1-2) , 65-71, (1990)

Interaction between anti-inflammatory drugs and reactive oxygen metabolites must be considered in the course of pharmacological studies intended to develop new compounds. Effects of indomethacin, aspirin, and 3,5-diisopropylsalicylic acid (3,5-DIPS) and their...

Fluorescence labelling of DNA by carboxylic polypyridyl-Ru complexes containing bpy and DIP ligands: a study revisited.

J. Fluoresc. 20(3) , 631-43, (2010)

The coordination complexes (DIP)(2)Ru(CH(3)bpyCOOH) and (DIP)(2)Ru(COOHbpyCOOH), where DIP and bpy are diphenylphenanthroline and bispyridine, have been recently proposed as fluorescent markers of nuclear DNA (Musatkina et al., J. Inorg. Biochem. 101:1086-108...

Synthesis and anticancer activity of lipophilic platinum(II) complexes of 3,5-diisopropylsalicylate.

Eur. J. Med. Chem. 43(7) , 1438-43, (2008)

Novel lipophilic platinum(II) complexes (LSPt-1-3), containing 3,5-diisopropylsalicylate (DIPS) as a leaving group and 2NH(3) or 1R,2R-diaminocyclohexane or (4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane as the carrier, have been synthesized, characte...

Deoxyribonuclease I is essential for DNA fragmentation induced by gamma radiation in mice.

Radiat. Res. 172(4) , 481-92, (2009)

Gamma radiation is known to induce cell death in several organs. This damage is associated with endonuclease-mediated DNA fragmentation; however, the enzyme that produces the latter and is likely to cause cell death is unknown. To determine whether the most a...

Fabrication and mechanical properties of PLLA/PCL/HA composites via a biomimetic, dip coating, and hot compression procedure.

J. Mater. Sci. Mater. Med. 21(6) , 1845-54, (2010)

Currently, the bone-repair biomaterials market is dominated by high modulus metals and their alloys. The problem of stress-shielding, which results from elastic modulus mismatch between these metallic materials and natural bone, has stimulated increasing rese...

Activation of calcium-dependent calmodulin by calcium(II)3(3,5-diisopropylsalicylate)6(H2O)6 decreases thrombin receptor activating peptide-induced P-selectin expression.

Blood Coagul. Fibrinolysis 14(2) , 131-8, (2003)

We examined the influence of 3,5-diisopropylsalicylic acid (3,5-DIPS) and calcium(II)3 (3,5-diisopropylsalicylate)6 (H2 O)6 [Ca(II)3 (3,5-DIPS)6 ], a new activator of calcium-dependent calmodulin-triggered nitric oxide synthase, on thrombin-induced platelet P...

Non-covalently aggregated zinc and cadmium complexes derived from substituted aromatic carboxylic acids: Synthesis, spectroscopy, and structural studies. Palanisami N, et al.

Inorganica Chim. Acta 405 , 522-531, (2013)