4-(Chloromethyl)benzoic acid

4-(Chloromethyl)benzoic acid Structure
4-(Chloromethyl)benzoic acid structure
Common Name 4-(Chloromethyl)benzoic acid
CAS Number 1642-81-5 Molecular Weight 170.593
Density 1.3±0.1 g/cm3 Boiling Point 317.7±25.0 °C at 760 mmHg
Molecular Formula C8H7ClO2 Melting Point 201-202 °C(lit.)
MSDS Chinese USA Flash Point 145.9±23.2 °C
Symbol GHS05 GHS08
GHS05, GHS08
Signal Word Danger

Improved gate effect enantioselectivity of phenylalanine-imprinted polymers in water by blending crosslinkers.

Anal. Chim. Acta 862 , 77-85, (2015)

In this work, the anodic current at an electrode grafted with a molecularly imprinted polymer (MIP) crosslinked via a combination of hydrophobic ethyleneglycol dimethacrylate (EDMA) and hydrophilic methylene bisacrylamide (MBAA) was found to exhibit enantiose...

Design, synthesis, and discovery of stilbene derivatives based on lithospermic acid B as potent protein tyrosine phosphatase 1B inhibitors.

Bioorg. Med. Chem. Lett. 17 , 4481-6, (2007)

Dihydroxy stilbene derivatives were designed based on lithospermic acid B and were prepared from 4-(chloromethyl)benzoic acid. The inhibitory activities of the novel compounds against protein tyrosine phosphatase 1B (PTP1B) were evaluated. 3,4-Dihydroxy stilb...

Synthesis of nitroaromatic compounds as potential anticancer agents.

Anticancer Agents Med. Chem. 15(2) , 206-16, (2015)

Twenty-seven nitrated and non-nitrated compounds have been synthesized and tested for their growth inhibitory activity on three human cancer cells lines. Fourteen compounds were able to inhibit more than 50% of the growth of at least one of the cancer cell li...