Methylenebis(Phosphonic Dichloride)
Methylenebis(Phosphonic Dichloride) structure
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Common Name | Methylenebis(Phosphonic Dichloride) | ||
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| CAS Number | 1499-29-2 | Molecular Weight | 249.78500 | |
| Density | 1.798g/cm3 | Boiling Point | 329ºC at 760 mmHg | |
| Molecular Formula | CH2Cl4O2P2 | Melting Point | 102-104ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 152.8ºC | |
| Symbol |
GHS05 |
Signal Word | Danger | |
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SYNTHESIS OF SYMMETRICAL METHYLENEBIS(ALKYL HYDROGEN PHOSPHONATES) BY SELECTIVE CLEAVAGE OF METHYLENEBIS(DIALKYL PHOSPHONATES) WITH MORPHOLINE.
Synth. Commun. 34(2) , 331-344, (2004) The preparation of partial esters of methylenebisphosphonic acids has been of recent interest due to their potential therapeutic applications. This paper describes a convenient method to prepare symmetrical methylenebis(alkyl hydrogen phosphonates) by the sel... |
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Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia.
J. Med. Chem. 45(3) , 703-12, (2002) Novel mycophenolic adenine dinucleotide (MAD) analogues have been prepared as potential inhibitors of inosine monophosphate dehydrogenase (IMPDH). MAD analogues resemble nicotinamide adenine dinucleotide binding at the cofactor binding domain of IMPDH; howeve... |
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A direct method for the synthesis of nucleoside 5'-methylenebis (phosphonate) s from nucleosides. Kalek M, et al.
Tetrahedron Lett. 46(!4) , 2417-21, (2005)
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Facile high yielding synthesis of symmetric esters of methylenebisphosphonic acid. Stepinski DC, et al.
Tetrahedron 57(41) , 8637-45, (2001)
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